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The Antarctic lakes are a “treasure trove” of unknown microbes that play critical roles in environmental processes … biosphere), including the global carbon cycle. The JGI is sequencing large numbers of microbes and microbial communities that contribute to carbon …

… things, because a lot of what we do at JGI in terms of the sequencing that we do is very people-disconnected, and … and take soil and discover a new important drug from the microbes in that soil, there are now international … methicillin-resistant Staphylococcus aureus . Can you share why finding treatments for these microbes is so important? …

NIGEL MOUNCEY: Oh, sure. I think our legacy obviously is in sequencing.  DAN: Of course.  NIGEL MOUNCEY: Sequencing the wazoo out of anything that’s relevant to the … But they really span our core science programs which are microbes, and fungi, and algae plants, synthetic biology. …

… sequence analysis to recover the genomes of uncultivated microbes. We also apply labeling strategies that allow us to select specific uncultivated microbes for sequencing based on their level of metabolic activity …

… variety of experimental samples, including organisms (e.g. microbes, fungi, plant), media in which they grow, as well …

… of Energy.   The JGI provides integrated high-throughput sequencing, DNA design and synthesis, metabolomics and … created in 1997 to unite the expertise and resources in DNA sequencing, informatics, and technology development … Science Program, characterize organisms (plants and microbes) relevant to the DOE science mission areas of …

… to DOE mission is appropriate. For accepted proposals, sequencing, synthesis, metabolomics and analysis will be …

… science by generating data in three overarching categories: Sequencing, Synthesis and Metabolomics. Strong internal …

A Letter of Intent is required. For accepted proposals, sequencing, synthesis, metabolomics and analysis will be …

… form and are reviewed annually. For accepted proposals, sequencing, synthesis, metabolomics and analysis will be …

… development of automated analysis pipelines for standard sequencing products performed at scale. Our group also …

… applied mini-metagenomics to these samples by sorting the microbes into small pools of cells that were then sequenced … and cleanup. The JGI provides integrated high-throughput sequencing and computational analysis that enable …