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Natural Prodcast Episode 16: Marcy Balunas
… know that that’s ever necessarily like a good description of anyone because chemistry means a lot, especially when … And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much … transfer. And so it’s beneficial then to have secondary metabolism in proximity within the genome so that things can …
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Mapping Heat Resistance in Yeasts
… A new approach for improving functional annotation in fungal genomes. The Science In a proof-of-concept study, researchers demonstrated that a new … biofuel production. Efforts such as the 1000 Fungal Genomics Project led by the DOE Joint Genome Institute … The work conducted by the US Department of Energy Joint Genome Institute, a DOE Office of Science …
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Data Policy
… Data produced and released by the US Department of Energy (DOE) Joint Genome Institute (JGI) are subject to the following Data … the need to have a limited and time-sensitive protection of certain types of data to support their use by those … PIs or co-PIs) who wish to include use-restricted data in publications, or who wish to redistribute data in any way …
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DOE Metrics
… FY 2026 DOE Metrics Sequencing Quarter Total Bases (Trillions) Operating Hours Goal  Actual Total*   Actual % of Goal   Goal (hours)**   Actual Total   Actual % Goal   FY … platforms. **Operating Hours target is based on 98% of the total available hours.   FY 2025 DOE Metrics There …
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Strain Engineering
… The focus of this group, in recent years, has been to bring generalizable technologies to bacteria, yeasts and algae previously with little to no genetic tools enabling heterologous expression and functional exploration.  The developed strains represent an …
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A Redesign for Yeast’s Genome, Chromosome by Chromosome
… To engineer yeast to do more, and understand genomes in general, Jef Boeke, Weimin Zhang (NYU Langone Health) and Leslie Mitchell (Neochromosome) have worked to replace yeast’s native chromosomes with synthetic versions. This …
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Natural Prodcast Episode 8: Eric Schmidt
… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … a podcast about the science and scientists of secondary metabolism.  DAN: Hey there and welcome back for Episode 8 … you’d like to read more about this, I highly recommend his publication last year, “The Biosynthetic Diversity of the …
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Metabolomics Technology Group
… Our lab is using mass spectrometry based metabolite profiling to provide … datasets to improve our understanding of microbial metabolism. Of particular interest is understanding the …
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A Cost-Efficient Way to Convert Yeast into a Cell Factory for Hydroxyapatite
… Innovative technology from this biomanufacturing … products from human waste. They   genetically modified yeast to efficiently convert elements present in urine to … hydroxyapatite, a high-value biomaterial with a wide range of industrial applications. The team was led by researchers …
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FICUS Overview
… The Facilities Integrating Collaborations for User Science (FICUS) … to more easily integrate the expertise and capabilities of multiple Department of Energy Office of Science National … provides customized analysis, the JGI also participates in publication of results. …
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Natural Prodcast Episode 3: The Primer, Part 3
… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the science and scientists of secondary metabolism.  DAN: Hey there. This is Dan again, and you’re … of biology. You know, I’ve personally been able to work in genomics, in protein structure, in synthetic biology, …
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Validating genome-wide CRISPR-Cas9 function improves screening in the oleaginous yeast Yarrowia lipolytica
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