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… … DAN: Welcome back for episode 9 of Natural Prodcast. This week, Alison and I talk to Roger … And that’s been followed by developments in pulse sequences and improvements in the ways in which you acquire … operate, and how analytes are produced, right through to applications and how you use that information in the most …

JGI Mission As a U.S. Department of Energy Office of Science user facility supported by the … metabolomics and computational analysis that enable systems-based scientific approaches to these challenges.     Our … in doing so enabled the JGI to be the first to publish the sequence analysis of the target chromosomes 5, 16, and 19, …

… … DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast– a … over time– for example, because of technologies or uses or applications– are the evolutionary nature of these … of natural product biosynthesis in bacteria ” The ActDES publication came out after we talked. It looks like a great …

… ,  Science Focus Areas  (SFA) opportunities, and the  Office of Science Early Career Research Program .   If … capabilities and products . A minimum request of 1 Tb of sequence data is required to qualify for BERSS. For DNA … submit proposals here . Investigators preparing grant applications to DOE-BER and requesting an optional letter of …

The JGI’s DNA Synthesis Program supports a wide range of projects, from single-gene synthesis to the synthesis of … and whole chromosomes for bioenergy and bioproduct applications. The program has completed over 70 projects, … Program aims to generate large datasets to explore sequence-function relationships, advancing the discovery of …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … turns a peptide, for example, from a disordered sequence into an antibiotic that kills bacteria through a … you’d like to read more about this, I highly recommend his publication last year, “The Biosynthetic Diversity of the …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … live in the root nodules of plants. And these guys were sequenced, and you can see that different Frankia have … I did want to impress, too, is that secondary metabolism is based on primary metabolism. It’s an evolution of primary …

Undergraduate Research Experience (CURE) that consists of coordinated hands-on experiments across fungal biology … and distribution of fungal genome datasets. It includes JGI-sequenced and publicly available datasets encompassing a … understanding of fungal diversity, ecology, and potential applications. … The Department of Energy Systems Biology …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … see things that maybe aren’t real, and so it’s thought that based on historical records and weather recordings of the …

The Facilities Integrating Collaborations for User Science (FICUS) … to more easily integrate the expertise and capabilities of multiple Department of Energy Office of Science National … provides customized analysis, the JGI also participates in publication of results. … All proposals undergo technical …

… schedule. This should be coming out on the first Thursday of the month, just like I promised. Now I just have to make … JACKIE: So they're very much developed their own language based on-- DAN: Sure. JACKIE: Yeah, they've evolved. That's … usually serve as dimers, and then they will bind to certain sequences of DNA. And when they bind to those certain …

… … Dan Udwary: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a … about the basics of genome mining, which is using DNA sequence to identify and interpret biosynthetic, secondary … all connected. And you can color these nodes. For example, based on taxonomy, or based on class of biosynthetic …