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… what we’re calling a Primer. We wanted to try and give a general audience some of the basics of natural products … knowledge of modern biology. We’re trying to keep this as general as possible, but scientists love technical jargon. … was adjacent to what I worked on, but my experience of how microbes are interacting in the environment like, like my …

… algae and plants. These compounds are key to organisms' interactions with their environments and with each other, … conditions, with only a small portion of the biosynthetic gene clusters (BGCs) being expressed. The program works to … uncover these hidden biochemical resources by exploring the genetic pathways responsible for their synthesis. The …

The Micro-Scale Applications group explores the genetic makeup of natural microbial communities using a … functional assay lets us move beyond cataloging the genes of microorganisms and start making quantitative … sequence analysis to recover the genomes of uncultivated microbes. We also apply labeling strategies that allow us to …

… percentile*) DNA Synthesis Constructs <5kb in size Single gene or multiple small genes assembled to less than 5kb in length, cloned into … clone 102/NA DNA Synthesis Constructs 5-10kb in size Single gene or multiple small genes assembled totaling 5-10kb in …

Pro Tips for Successful Community Science Program (CSP) Applications Webinar inviting researchers to submit white papers to the CSP  New Investigator call for proposals.  Tips: Contact us … genomics in support of DOE missions related to clean energy generation and environmental characterization and cleanup. …

In the ocean’s North Pacific Subtropical Gyre, microbes tend to stay localized at different depths. But … to determine the genome structure of SAR324 cells and their gene expression, the team then sequenced community genomes and expressed gene transcripts (metagenomes, metatranscriptomes), as well …

… that they needed to consider chemical impact on species interactions, communication, that kind of thing. But … the most effective application, of marine molecules in general. DAN UDWARY: Maybe can you explain to our audience … you think about the fact that, when plants and animals and microbes evolve, they evolve to make molecules that improve …

… and characterize genomic information from uncultivated microbes and viruses. We develop computational approaches to … Ladau, J. et al. (2019)  Spatial, Temporal, and Phylogenetic Scales of Microbial Ecology . Trends Microbiol. …

… project manager Miranda Harmon-Smith, who helps shepherd CSP projects along. …

… technology to help access complicated natural product gene clusters, and we’re all really excited about that, and … that we are working on into perspective in the field in general. So what has happened in the past two decades is … total, and different people have different numbers, but in general, an authoritative number for total number of natural …

… come from livestock — specifically, from the methane-making microbes within their rumen. There is another climate-minded … to understand. A better understanding of rumen and the microbes that live there can drive solutions into stemming … around the world to map out genomes of rumen microbes. In 2018, through a JGI Community Science Program proposal that …

… while nurturing a fresh cohort of users Reach the next generation of genome scientists and recruit new talent for …