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… A team has optimized a crucial part of CRISPR-Cas9 technology to enable improvements in … their tool before felling their research problem: at a genetic level, how does  Y. lipolytica work? The project was … an initial screen using an unvetted library (with both active and inactive sgRNAs) appeared to be rife with false …

… system traces polyploid genome evolution. Flowering plants abide by the concept, “the more the merrier,” … plants; at least once during their evolution, the genomes of flowering plants multiply. Over time, plants lose many … than any individual genome highlighting the fact that the genetic information in a single reference genome is …

… In a special issue of mSystems , out May 14, 2019, JGI researchers are among the authors who offer perspectives on what the next five years of innovation … incubating DNA with isotopically-labeled compounds to link active microbes with specific metabolic processes. A third …

… Kaushal Sharma, one of five Antioch High School rising juniors who participated in internships at the DOE Joint … program is now an author on a Nucleic Acids Research publication. The paper describes the version 6 data updates …

… Register here Book your stay at the conference venue This inaugural event will bring together researchers across major … and applying laboratory ecosystems to help transition microbiome science from largely observational to … studies.  This conference is inspired by the vision of standardized fabricated ecosystems (EcoFABs) designed for …

… survival, may now be easier to characterize following a proof-of-concept study in which researchers paired CRISPR and … is a technique researchers can use to integrate large genetic payloads directly into diverse microbes. Combining … the researchers used CRAGE-CRISPR for discovering active secondary metabolites and helping them identify and …

… Maureen Coleman and Hugh Cross; [Below] Zac Freedman, Martin Jonikas, Lotus Lofgren, Fumito Maruyama, Lauren Stadler, Tingting Xiang and … enzymes discovered in extreme environments to engineered microbiomes that accelerate biomass processing. This year’s …