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… New evidence shows anaerobic fungi can degrade the hardiest of plant components   The Science There are three main … anaerobic fungi (Neocallimastix californiae) on sorghum, switchgrass and poplar, then monitored changes to the … JGI data portals and pipelines helped identify potential genes responsible for lignin deconstruction. (The JGI also …

… Gene expression in eukaryotes was long held to be … a single protein. Recently reported in the Proceedings of the National Academy of Sciences , a team of researchers has found numerous … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …

… from single cells. The Science Studying the  genomes of microorganisms is incredibly useful for understanding the … way of collecting them is through a method called Multiple Displacement Amplification, and most genomes that … it’s difficult to link the connections to them from the genetic elements that scientists have found, e.g. plasmids …

… (CSP) . This includes mass spectrometry-based measurements of primary and secondary metabolites from plants, … et al.  MAGI: A Method for Metabolite Annotation and Gene Integration . ACS Chem Biol. 2019 Apr 19;14(4):704-714. … samples and test how many they thought would be necessary. Switchgrass has an enormous metabolome, and we wanted to …

… Department at the Joint Genome Institute. His team of engineers and scientists builds and operates the data and … science.  Dr. Sneddon is an accomplished leader in data, software, compute, and AI for large-scale genomics and lab … Prior to joining JGI in late 2025, he served as Director of Scientific Computing at Predicine, an NGS-based clinical …

… Large-scale comparative analysis leads to identification of biosynthetic gene clusters for novel secondary metabolites for multiple applications. Despite advances in sequencing … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science … genomics in support of DOE missions related to clean energy generation and environmental characterization and cleanup. …

… JGI is in the process of shifting its operations from Walnut Creek to the heart of … labs in one long building at Walnut Creek, after countless generations of sequencing platforms (up to 120 sequencing … Walnut Creek and deciding on what was essential. There were multiple waste streams to consider, including unneeded …

… While summer interns at the JGI from multiple programs had their own goals to achieve, they constantly collaborated with each other on new ways of presenting and researching science. …

… project to form new connections between fungal guilds, genes and function. If a tree falls in the forest — whether … registers the sound — one thing is for sure: there are lots of fungi around. Within a forest’s soil, hundreds of species … Head at the JGI.  Along with an improved understanding of multiple forest systems, this work sets up protocols and …

… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and … refine and improve the process of finding novel Cas genes and CRISPR systems. The collaboration has resulted in … Combining forces with UC Berkeley to seek elusive gene-editing proteins …