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Neha Varghese
… and implementation of microservices in conjunction with the IMG platform. …
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Zhong Wang
… scientists and biostatisticians. Through collaborations with internal and external scientists, the Wang group has …
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Expanding Virophage Diversity
Virophages are small viruses with double-stranded DNA genomes that co-infect eukaryotic cells along with giant viruses. Virophages are small viruses with double-stranded DNA genomes that co-infect eukaryotic …
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Jeremy Schmutz
Mr. Schmutz’s involvement with the DOE Joint Genome Institute dates back to 1997, when …
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Nigel Mouncey
… a long-standing interest in microbial genetics that started with his education and carried forward into his roles as a … 2022. Expanding the Genomic Encyclopedia of Actinobacteria with 824 Isolate Reference Genomes. Cell Genomics 2: … 33 pending. Includes: Enhancing spinosyn production with oxygen binding proteins. (2014) U.S. Patent Application …
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
With a new methodology, scientists are now getting more … these scientists (now at Stanford University) collaborated with the JGI. Working together, they found most bacterial … soil communities were at least 80% complete when studied with PTA, compared to <30% complete when studied with MDA. …
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Better Genome Editing for Bioenergy
… of researchers sought to disrupt every gene in the genome with CRISPR-Cas9 in order to interrogate each one’s … to fix a defect in the approach: CRISPR-Cas9 relies on RNA with a short guiding sequence (20 bp) that directs the … cut, but these “single guide” RNAs (sgRNAs) can be faulty. Without a good sgRNA, Cas9 is ineffective and leaves the …
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An Inside Look at How Plants and Mycorrhizal Fungi Cooperate
… carbon into soil and boosting biofuel feedstocks with less fertilizer. For millions of years, underground fungi have lived in symbiosis with plant roots. Plants provide photosynthesized carbon, … two cell types [of two different organisms] are interacting with each other, without all the noise or other biological …
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An Inside Look at How Plants and Mycorrhizal Fungi Cooperate
… carbon into soil and boosting biofuel feedstocks with less fertilizer. For millions of years, underground fungi have lived in symbiosis with plant roots. Plants provide photosynthesized carbon, … two cell types [of two different organisms] are interacting with each other, without all the noise or other biological …
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Triggering Morel Fruiting
… the fruiting-related decomposition mechanisms of morel with multi-omic approaches, our results revealed a striking … the key physiological factors that trigger forest mushrooms with diverse trophic modes to convert from vegetative …
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Boosting Small Molecule Production in Super “Soup”
… (Spoiler: Yes.) Think of cells as tiny factories: within their walls they have both the machinery to make … University describe a two-pronged approach that starts with engineered yeast cells but then moves out of the cell … products in industry.” From Cell to “Soup” The work started with yeast strains engineered by Alper’s team to convert the …
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The Expanding Universe of Methane Metabolisms in Archaea
… that methanogenesis is one of the oldest metabolisms, with the first traces possibly at ~3.5 Gy (billion years),” … the other five only distantly related to known methanogens. With the help of this information, the researchers found … genes that serve as a core set of genes present in archaea with metabolisms involving methyl-coenzyme M reductase …
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