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The DOE Joint Genome Institute hosted the hybrid “NeLLi 2023 … Overview of Symposium Goals Metagenomic and single-cell sequence data have provided a means to access novel … This symposium series will provide an overview of the bacterial, archaeal and microeukaryote diversity cataloged …

Dr. I-Min A. Chen received her Ph.D. in Computer Science. Her research has been focused on semantic and object-oriented data modeling, and biological data management. She was one of the …

Microbial cells infected by viruses undergo metabolic reprogramming. The … in one proposed research project. For this project, RNA sequencing was done by the JGI, and proteomics and … approach to infecting and metabolically reprogramming the bacterial host, which was transformed into two very …

Scientists find bee gut microbes have a division of labor when it comes … yield sugar monomers, it’s only with the aid of specialized bacterial enzymes. Honey bees rely on their gut microbiota … and cleanup. The JGI provides integrated high-throughput sequencing and computational analysis that enable …

A “bait and hook” single-cell genomic approach to bioprospecting. The Science … pools, followed by whole genome amplification and shotgun sequencing. The team first tested the approach on bacterial laboratory models to set a reference for its …

… cultures reveal they are symbionts and not free-living organisms. The Science Researchers employed multiple … biosphere), including the global carbon cycle. The JGI is sequencing large numbers of microbes and microbial … in understanding the genomic basis and ecological consequences of microbe-microbe interactions. Using metagenomes …

Antarctic algae need their vitamins; zinc fuels some of their most important functions. Even … collaboration, in 2017, they published the first genome sequence of a cold-adapted microalga: the diatom … and cleanup. The JGI provides integrated high-throughput sequencing and computational analysis that enable …

With a new methodology, scientists are now getting more complete genomic results from single cells. The … usually employ two different methods; shotgun metagenomic sequencing and single-cell sequencing. For years, extracting … with the JGI. Working together, they found most bacterial genomes from water and soil communities were at …

… warm-adapted microbes edge polewards, they’d oust resident tiny algae. The cold polar oceans give rise to some of the … than previously suspected. “That would cause significant consequences on the entire food web, and therefore ecosystem … After isolating the algal communities on filters, they sequenced DNA ‘marker’ gene sequences to identify the …

For many scientists, the culmination of their work into a written report that is published in a scientific … applications, Wint also developed and tested a gene sequence-based predictor of gene expression levels using …

… part of CRISPR-Cas9 technology to enable improvements in microbial oil production. The Science CRISPR-Cas9 is a … Cas9 needs guide RNA to lead it to the correct sequence to snip — but not all guides are effective. To … approach: CRISPR-Cas9 relies on RNA with a short guiding sequence (20 bp) that directs the endonuclease where to cut, …