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JGI@25 RECAP: 2022 Annual Meeting features historical perspectives on JGI’s 25 years
… concepts.” Patrinos went on to explain that the JGI’s very first project — the revolutionary work of the human genome … so there was quite a bit of resistance to use resources to sequence it,” Patrinos said. After many more meetings and … focused around how to best work together to achieve great success. “For the most difficult challenges, no one agency has …
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Busting the Unbreakable Lignin
… clues left some researchers wondering if perhaps the accepted narrative wasn’t quite accurate, and maybe anaerobic … (The JGI also conducted RNA sequencing and alignment to the reference fungal  genome . The study’s pivotal NMR (nuclear … in the absence of oxygen. These findings offer the first real irrefutable proof that lignin can be …
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JGI@25: A Single Cell, Myriad Microbial Discoveries
… for Ocean Sciences described a novel technique to access high-quality genomic information using minute … which remains unknown and uncultured in laboratories. Other firsts followed. The next year, the JGI team reported the … cell (seen here in a glass capillary), researchers sequenced and assembled the first complete genome of an …
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Crops as Tough as World Cup Turf
… crops.  One grass they studied just happened to be the same species that covered World Cup pitches in 2022.                     …
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Mapping Heat Resistance in Yeasts
… promote heat resistance in the brewer’s/baker’s yeast Saccharomyces cerevisiae , allowing this species to grow … (RH-Seq). Strains of S. cerevisiae and S. paradoxus were first used to create a sterile interspecific hybrid. In this … then used a series of random insertions of a foreign DNA sequence to generate a huge pool of mutants, each containing …
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Expanding Virophage Diversity
… increased the number of known high quality virophage genome sequences 10-fold through computational approaches. By … virophage marker gene MCP, they were able to identify 44,221 total virophage partial sequences, including over 28,000 … rhizosphere, wastewater, and even animal and human (for the first time) gut and taxonomically classified into 27 …
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GenomeOcean Leverages AI to Decode Nature’s Secret Language
… community able to not just analyze but also create DNA sequences mimicking an array of microbial life. By … data, GenomeOcean employs artificial intelligence for cutting-edge genomic research — and is capable of … the data it is trained on,” Wang said. “Most models rely on reference genomes to train genome foundation models. …
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RECAP: Keynote Speakers Talk Innovation at 2022 JGI Annual Meeting
… team is looking to use CRISPR-Cas9 to solve new problems. According to Doudna, the CRISPR-Cas9 investigations began as … Jill Banfield approached Doudna with repeated genetic sequences (already known as CRISPR) that came up in her … work paved the way to move beyond a single case-study, the reference genome, to something that represents all of the …
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John Vogel
… Dr. Vogel joined JGI in 2014 to establish a plant functional genomics program. Prior … served as a Research Molecular Biologist at the USDA for 12 years where he was a driving force behind the development … on developing plant functional genomic resources (e.g. sequenced mutant collections, transformation technology, …
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Plant Program
… gene annotation and protein folding models, to improve the accuracy of functional predictions and speed up genome … yields and support ecosystem health. By integrating cutting-edge technologies and data-driven methods, the … drives major phenotypic differences in plants and will accelerate gene discovery. BrachyPan on Phytozome (see …
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Metatranscriptomic Sequencing of a Cyanobacterial Soil-Surface Consortium with and without a Diverse Underlying Soil Microbiome
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