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Researching and Solving Real-World Problems with the 2023 JGI-UC Merced Interns
… For the first time in several years, the DOE Joint Genome Institute hosted … students this past summer. This year’s cohort for the JGI-UC Merced Internship Program was brimming with …
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Accelerating Metagenomics Discoveries with Deep Learning
… Berkeley National Laboratory (Berkeley Lab) and other institutions shared their works-in-progress with 86 participants in an online workshop to … the US Department of Energy (DOE) Joint Genome Institute (JGI), presented on generating vector representations of …
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First Monoploid Reference Sequence of Sugarcane
… and have two sets of chromosomes, one from each parent. In contrast, many crops have multiple sets of chromosomes … polyploid sugarcane genome now underway as part of the JGI Community Science Program (CSP), a critical factor in … reference of the gene-rich part of the sugarcane genome. Reported in Nature Communications , their approach relied in …
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Green Algae Reveal One mRNA Encodes Many Proteins
… Gene expression in eukaryotes was long held to be monocistronic – that is, a … messenger RNA, which encodes a single protein. Recently reported in the Proceedings of the National Academy of … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at …
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JGI-Enabled Research Demonstrates the Existence of New Methane-Makers
… gas, regulate Earth’s climate. Most methane is produced in environments without oxygen through a process called … Methanogenic microorganisms therefore play a critical role in the global carbon cycle, and are of significant interest … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at …
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Computationally Classifying Fungal Lifestyles
… Machine learning methods were applied on sequenced fungal … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … the data provided. In this proof of concept test, the team reported that the algorithm was over 95% successful at …
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How Maize Makes An Antibiotic Cocktail
… Maize produces a family of compounds that protects it against infections — using surprisingly few enzymes. The … scientists a bigger bang for their buck. The research team reports that transferring just four genes encoding these … as  Sorghum bicolor — a  candidate bioenergy feedstock and  JGI Flagship Plant — could produce at least 15 zealexins. …
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The Mobilome in the Mire
…   For years, researchers have known that many datasets miss a key … MGEs, that can move between organisms. But now, deep sequencing and new analysis methods are bringing this mobilome into … Bagby (Case Western Reserve University) and Simon Roux (JGI) as they talk about their recent work on a time series …
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Jane Grimwood Named HudsonAlpha Genomics Chair
… Congratulations to Jane Grimwood, who has been appointed the Loretta Purdy Spencer Chair in Genomics at the … Grimwood heads the Library Construction group for the JGI Plant Program . Her collaborations with the JGI began … the simplest cotton genome ( Gossypium raimondii ) several years ago.   As well as the seminal Human Genome Project DOE …
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An Addiction Crucial to a Fungus’ Reproduction
… bacteria to regulate key components of its reproductive machinery The Science To better understand how beneficial … and experimented with the fungi and bacteria, while the DOE JGI team sequenced and annotated a host genome (Rm ATCC 52813) as part of the 1000 Fungal Genomes project. As reported in the November 29, 2017 issue of Nature …
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Fishing for Novel Cellulose Degraders
… A “bait and hook” single-cell genomic approach to bioprospecting. The Science … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … spectrometry-based enzyme activity assay. The work was  reported in  The ISME Journal . While the screen caught …
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Improved High-Quality Draft Genome Sequence of the Eurypsychrophile Rhodotorula sp. JG1b, Isolated from Permafrost in the Hyperarid Upper-Elevation McMurdo Dry Valleys, Antarctica
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