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… 5,000 times bigger than most bacteria. To put it into context, it would be like a human encountering another human … at the Université des Antilles and a co-first author on the study, performed the 16S rRNA gene sequencing to identify … continue research on the project. At the JGI, Volland began studying Ca. T. magnifica in Tanja Woyke’s Single Cells …

Webinar held November 5, 2020 (watch the  video below, captions are available) spotlighted the metabolomic analysis … Q: Can you give us an idea about the scale of an average study? How many samples are typically involved? How long … Data Analysis – Tips from Users page.  Q:  Is the metabolic study able to build a profile for a not very well studied …

Fine-tuning metabolic gene expression helps identify variants in yeast genes. The Science … a more nuanced library approach to tuning gene expression in metabolic pathways. Compared to the traditional way, … optimization. Summary Life is all about balance. This study,  recently published in the  Proceedings of the …

A two-day kick-off meeting held at Lawrence Berkeley National Laboratory (Berkeley Lab) marked the visit of an esteemed interdisciplinary delegation from the University of Duisburg-Essen (UDE), Germany with … workshops. Of common interest is the method development to study active sites or single cells in their functional …

Tracking evolution of symbiotic lifestyles across multiple fungal lineages. … to establish symbiotic relationships with plants (mycorrhizae), and particularly how fungi that feed on decaying … (Berkeley Lab). All of the fungal genomes used in the study are available on the JGI fungal portal  MycoCosm . The …

RIViT-seq technology could speed up associating transcription factors with their target genes. The Science Regulons are … given sigma factor are inferred. Prior to this most recent study, only 12 sigma factors and 200 genes (or 209 sigma … to 399. Two of the 11 sigma factors addressed in the study were found to control more than 100 genes, one of …

By studying the structure and function of a cyanobacterial protein, researchers have new … insights into how these ocean photosynthesizers cycle carbon in changing conditions. The products of photosynthesis … scientist at the JGI and Molecular Foundry, and the study’s senior author. In other proteins, two histidine …

… of the DNA Synthesis Science Program since 2015. The mission of this program is to harness the power of DNA synthesis, … strain engineering, and biosystems design for DOE-mission-relevant discovery and applications. This program has supported over 250 projects since it …

… to ancestral bacteria’s energy sources. More than two billion years ago, cyanobacteria acquired the ability to produce … fellow Paula Matheus Carnevali was working with a group of metagenome-assembled genomes (MAGs) dubbed Margulisbacteria, … The research teams opted to collaborate on a single study, with Matheus Carnevali and Schulz sharing co-first …

… working for the Stanford Human Genome Center, now the HudsonAlpha Institute for Biotechnology. There he constructed the pipelines for directed finishing and co-led … DOE human chromosomes 5, 16, and 19. Following the completion of the human genome project in 2003, he developed …

In a recent  Nature Genetics paper , researchers focused on the full composition of genes, or pangenome, of the model plant  Marchantia polymorpha. Commonly known as liverwort, this was done to gain insights into …

… technology to enable improvements in microbial oil production. The Science CRISPR-Cas9 is a powerful, high-throughput … applications. Cas9 needs guide RNA to lead it to the correct sequence to snip — but not all guides are effective. … I will spend the first four sharpening the axe.” In this study,  published in  Metabolic Engineering , a team of …