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A Better Way to Find RNA Virus Needles in the Proverbial Database Haystacks
… to sift and characterize RNA virus sequences.  A zoo once offered a coloring book featuring polar bears in winter scenes that came with crayons in various shades of white. To researchers searching for sequences of RNA … a gene that encodes for an enzyme called RNS-directed RNA Polymerase (RdRP), necessary for replicating the RNA genome …
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Silver age of GOLD introduces new features
… sequencing projects carried out at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office … a broad range of activities from proposal intake to publication. Information is also obtained and cross-checked … entities,  further outlined in the journal  Nucleic Acids Research in November 2022.  One of GOLD’s strengths …
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Inspiring STEM Careers Through a Hands-on Everglades Microbiome Study
… Journal publication caps JGI pilot project with fledgling Florida … school scientists. The Florida Everglades evokes images of fanboats skimming over swamps, while alligators peer … able to tell the students that the paper was accepted for publication in a reputable scientific journal. It was …
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Axel Visel
… Programs, he focuses on the development and implementation of strategic initiatives at the JGI. Dr. Visel received his … methods for elucidating the gene regulatory landscape of vertebrate genomes, which led to the discovery of thousands of genetic switches implicated in developmental …
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John Vogel
… Dr. Vogel joined JGI in 2014 to establish a plant functional genomics program. Prior to this, he served as a … years where he was a driving force behind the development of numerous genomic resources that fostered the widespread … Dr. Vogel’s current research is focused on developing plant functional genomic resources (e.g. sequenced mutant …
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Jeremy Schmutz
… human chromosomes 5, 16, and 19. Following the completion of the Human Genome Project in 2003, he developed … assembly, and improvement strategies for de novo sequencing of eukaryotic organisms from simple yeasts to large … the JGI Plant Program, focusing on the organization of community driven science for JGI Plant Flagship Genomes …
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Model Fern Reveals Insight into DNA Thievery in Ferns
… — making it difficult to grasp a deeper understanding of fundamental aspects of fern biology and, more broadly, land plant evolution. … showed that genes directing development of reproductive structures in seed plants were essentially co-opted from … The work conducted by the US Department of Energy Joint Genome Institute is supported by the Office …
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Boosting Small Molecule Production in Super “Soup”
… still work in cell-free environments? (Spoiler: Yes.) Think of cells as tiny factories: within their walls they have … , researchers led by Hal Alper at The University of Texas at Austin and Michael Jewett of Northwestern … to produce the small molecules glycerol and itaconic acid to see how the cell-free system allowed them to …
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A New Actinobacterial Chapter in the Genomic Encyclopedia of Bacteria and Archaea
… Large-scale comparative analysis leads to identification of biosynthetic gene clusters for novel secondary … The planet’s microbial diversity is immense, yet much of it remains unknown. For more than a decade, researchers … resource, but also yielding and supporting many high-impact publications ,” emphasized Markus Göker, who managed the …
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Nigel Mouncey
… the fourth Director in its 27-year history. He has a wealth of managerial experience from almost 20 years in the … focused on the discovery, development and commercialization of novel production organisms and fermentation processes for … on secondary metabolites. He is also on the Leadership Team of the National Microbiome Data Collaborative and served as …
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Shattering Expectations: Novel Seed Dispersal Gene Found in Green Millet
… Survey of Setaria's natural diversity reveals seed dispersal in … Center (Danforth Center) drove up and down the highways of the continental United States, occasionally pulling over to the side of the road to collect small weedy plants and bring them … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …
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Len Pennacchio
… Joint Genome Institute and has focused on applying state-of-the-art molecular methods to address wide-ranging … Scientist at Lawrence Berkeley Laboratory, and Adjunct Professor at UC Berkeley. Dr. Pennacchio received his Ph.D in 1998 from the Department of Genetics at Stanford University where he uncovered the …
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