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A Complex Confection Decoded: Sugarcane Reference Genome
… the location of genes that provide resistance to the brown rust disease that can devastate a crop. The Impact In … foundational genetic information that crop breeders can use to improve sugarcane varieties and advance a sustainable bioeconomy. Researchers and farmers could improve …
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Mining Metagenomes for Cas Proteins
… The Science Researchers report the discovery of miniature Clustered Regularly Interspaced Short Palindromic Repeats … (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility. The sequences were then … across many areas. In particular, gene editing is being used to develop drought, flooding, pest-resistant, and …
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In Hot Spring Microbial Mat, Viruses Ride “Piggyback”
… first time, a team has comprehensively described host-virus dynamics in a microbial mat. The Science In microbial mats, communities of microorganisms live among viruses that infect them. But what trends govern those virus-host interactions? Do generalist viruses run rampant, …
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Soil virus offers insight into maintaining microorganisms
… Using the IMG/M data portal, researchers have identified a virus protein tied to carbon cycling.  The Science Through a … effort, researchers have identified a protein in soil viruses that may promote soil health. The work was enabled in … Research (BER) and is a contribution of the Scientific Focus Area “Phenotypic response of the soil microbiome to …
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Rex Malmstrom
… the ocean. Later during his postdoctoral work at the Massachusetts Institute of Technology he developed a high … bacterial cells and amplifying their genetic material, thus bypassing the need to culture these microbes in the lab. … a similar single-cell genomics pipeline that provides JGI users access to the genomes of uncultured microbes.  His …
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Supercomputing, MetaHipMer and the Mega Dataset of Lake Mendota
… technology has changed dramatically over the last  25-plus years since the JGI’s inception, making it possible for … computing infrastructure and analysis. This way, JGI users — both primary, data-generating users, as well as secondary, data-downloading users — have …
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The Power of One, Amplified
… genomics can add significant value to the other commonly used culture-independent sequencing approaches including … the planet’s nutrient cycles and are potentially of use in fields ranging from agriculture to biotechnology and … tools have helped decode the genomes of tens of thousands of previously unknown and uncultivated microbes …
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Triggering Morel Fruiting
… (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility,  reported on just how morel fruiting is triggered when nutrients are … every family of fungi. In the following guest piece, JGI user Dr. Tan details the results of the team’s work. Morels …
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Olpidium, The Key to the Origin of Terrestrial Fungi
… (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility, found that the fungus Olpidium is a link in the evolution and transition of … every family of fungi. In the following guest piece, JGI user Ying Chang in the Spatafora lab describes the effort …
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Gut Fungi: Unexpected Source of Novel Chemicals
… off early from aerobic fungi, which can breathe oxygen — just like we do. Oxygen is a rich source of energy, and because anaerobic fungi can’t harness it, scientists long held … source of antibiotics. Indeed, these anaerobic fungi may be using these compounds for self-defense. But the compounds …
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How Maize Makes An Antibiotic Cocktail
… a family of compounds that protects it against infections — using surprisingly few enzymes. The Science Maize ( Zea mays … scientists have identified at least 15 zealexins, they suspect there are even more to find. Zealexins are produced … a dozen enzymes. But researchers have now revealed that just a handful of enzymes are needed to transform zealexins …
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The Expanding Universe of Methane Metabolisms in Archaea
… insights into an ancient metabolism. Methane is a greenhouse gas 20 times more potent than carbon dioxide. Billions … (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility, for publicly available metagenome data … and short-chain alkane-oxidizing archaea. They used IMG because the database already contains metagenome …
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