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Olpidium, The Key to the Origin of Terrestrial Fungi
… (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility, found that the fungus Olpidium is a link in the evolution and transition of … every family of fungi. In the following guest piece, JGI user Ying Chang in the Spatafora lab describes the effort …
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Gut Fungi: Unexpected Source of Novel Chemicals
… off early from aerobic fungi, which can breathe oxygen — just like we do. Oxygen is a rich source of energy, and because anaerobic fungi can’t harness it, scientists long held … source of antibiotics. Indeed, these anaerobic fungi may be using these compounds for self-defense. But the compounds …
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How Maize Makes An Antibiotic Cocktail
… a family of compounds that protects it against infections — using surprisingly few enzymes. The Science Maize ( Zea mays … scientists have identified at least 15 zealexins, they suspect there are even more to find. Zealexins are produced … genes encoding these enzymes to another plant, such as  Sorghum bicolor — a  candidate bioenergy feedstock and  JGI …
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JGI@25: Expanding Metagenomics to Capture Viral Diversity
… will help solve energy and environmental challenges. Viruses are everywhere — in soil, the sea and, of course, the cells of other organisms. As they infect microbes like bacteria, algae and protists, all kinds of viruses impact many ecological processes, including carbon …
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Tanja Woyke Awarded van Niel International Prize for Studies in Bacterial Systematics
… 2013 Nature paper , which uncovered nearly 30 major previously uncharted branches of the tree of life. A senior … Lab), Woyke currently serves as the interim deputy for JGI User Programs. Earlier this year, she was elected to the …
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The Expanding Universe of Methane Metabolisms in Archaea
… insights into an ancient metabolism. Methane is a greenhouse gas 20 times more potent than carbon dioxide. Billions … (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility, for publicly available metagenome data … and short-chain alkane-oxidizing archaea. They used IMG because the database already contains metagenome …
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Hiroshi Otani
… particularly actinomycetes. His research activity is focused on developing and implementing new technologies and … Mouncey NJ. Comparative and pangenomic analysis of the genus Streptomyces. Sci Rep. 2022 Nov 7;12(1):18909. Otani H, … governs the principal sigma factor in Streptomyces griseus. Mol. Microbiol. 87, 1223-1236. PubMed …
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JGI@25: Solving the Mystery of the Missing Oil
… between.” To find an explanation, his team tracked the thousands of bacterial and archaeal species using a DNA-based array developed at Berkeley Lab. Over the …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… is central to our ability to offer host-engineering for our users,” says JGI Director Nigel Mouncey. Using CRAGE, JGI has established a portfolio of microbial hosts that users can select to be engineered. “Piloting access to this …
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Learning to Look
… Machine learning approach significantly expands inovirus diversity. To answer the question, “Where’s Waldo?” … (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility, developed an algorithm that a computer could … methods to discover new anti-CRISPRs,” said Adair Borges, a graduate student in bacterial immunologist Joe …
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JGI@25: A Single Cell, Myriad Microbial Discoveries
… novel technique to access high-quality genomic information using minute quantities of DNA derived from individual … microbial genomes that were mapped to nearly 30 major previously uncharted branches of the tree of life. Used in tandem over the years, metagenomics and single cell …
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Open Frameworks Training the Next Generation of Scientists
… participants. Over the past two years, Myco-Ed has been used in 15 individual classrooms across the country, … DOE Joint Genome Institute (JGI), a DOE Office of Science User Facility, and the DOE Systems Biology Knowledgebase … It’s a key problem to solve because fungi are very diverse organisms with potential biotechnology applications in a …
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