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… user engagement. The Science In addition to the core set of "primary metabolites"—chemical compounds shared by most … in the recent Database issue of the journal Nucleic Acids Research , the Secondary Metabolism Collaboratory … more than 13 million BGCs in the catalog at the time of publication, it is the largest repository of BGC sequence …

… Institute.  The Science Researchers report the discovery of miniature Clustered Regularly Interspaced Short … now at Tel Aviv University. The Cas14 proteins are ~400–700 amino acids (aa) in size, half that of previously known class 2 … The work conducted by the US Department of Energy Joint Genome Institute, a DOE Office of Science …

… Describing the largest analysis to date of the modified DNA base 5mC variations in fungi. The … T or G in a genome sequence can lead to changes in protein structures and functions, but the DNA bases themselves can also be … The work conducted by the US Department of Energy Joint Genome Institute, a DOE Office of Science …

… his backyard in Tennessee — the birds are chirping and a soft breeze ripples through the trees in his backyard. Originally from northern California and one of the first students to participate in the DOE Joint Genome … fine tune his approach. “I got a lot of that from Zhong.”   Publication: Carrell AA et al. Habitat-adapted microbial …

… A team has optimized a crucial part of CRISPR-Cas9 technology to enable improvements in … biomass carbohydrates — glucose and xylose — into fatty acids that could be used for renewable fuel. In fact, lipids … genome with CRISPR-Cas9 in order to interrogate each one’s function. However, the team first needed to fix a defect in …

… Dr. Yasuo Yoshikuni has been head of the DNA Synthesis Science Program since 2015. The mission of this program is to harness the power of DNA synthesis, strain engineering, and biosystems design … at the JGI. Click to learn more about the program's areas of focus, major initiatives and more.  …