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… . The Science A team led by researchers at the University of California, Berkeley used a multi-omics approach to … researchers at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … other organizations. … We acknowledge the use of deletion strains generated by Grant P01 GM-068087 “Functional …

… that allows researchers to quickly modify diverse bacterial genomes. In 2019, the JGI’s Yasuo Yoshikuni and his team  … ( CRAGE ). CRAGE enables scientists to insert large pieces of DNA (up to 60 kb) in a single step, directly into the … domesticate some 60 strains, inserting into them a genetic sequence that acts as a “landing pad.” Mouncey adds, “Once …

… more than 13 million BGCs in the catalog at the time of publication, it is the largest repository of BGC sequence data from over 1.3 million publicly available bacterial and archaeal genome and contig sources.  The Impact Secondary metabolites …

The Impact The Antarctic lakes are a “treasure trove” of unknown microbes that play critical roles in … in understanding the genomic basis and ecological consequences of microbe-microbe interactions. Using metagenomes recovered directly from environmental samples and …

… researchers built an interactive and comprehensive database of fermentative prokaryotes. The Science Most organisms use … including the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … phenotype and genotype of fermentative prokaryotes on IMG … Publication … Datasets … Datasets … Datasets …