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Innovative Technology Improves Our Understanding of Bacterial Cell Signaling
… developed chemiluminescent biosensors shed light on how bacteria function and colonize diverse environments. The … di-GMP (Guanine Monophosphate) is found in nearly all types of bacteria and interacts with cell signaling networks that … YcgR proteins and chose a set of 92 proteins for functional characterization as candidate biosensors. These 92 …
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Waiting to Respire
… Genomes from uncultivated bacteria offers clues to ancestral bacteria’s energy … shaped the evolution of life on Earth, and led to the development of multicellular organisms. Not all bacterial … related to clean energy generation and environmental characterization and cleanup. The JGI provides integrated …
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2024 Progress Report
… The Integrative Genomics Building (IGB) seen above is home to the DOE … for a sustainable bioeconomy. Mission  As a U.S. Department of Energy Office of Science user facility, we provide advanced genomic … processed 13,700 metabolomics samples With our users, 247 publications were published   …
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JGI@25: The Human Genome Project, or the JGI’s Origin Story
… In honor of the JGI's 25th anniversary in 2022, we have revisited a … They wanted to learn about the genes implicated in the development of breast and prostate cancer, and Crohn’s … with the HudsonAlpha Institute for Biotechnology.   Publications Grimwood, J., Gordon, L., Olsen, A. et al. The …
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Taking Stock of the Known and Unknown Microbial Space
… Metagenomic datasets could help map out microbial diversity … in sequencing technologies have led to an abundance of microbial genomes becoming available to the global … in Science Advances , researchers at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office …
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JGI-UC Merced Interns Share Their 2021 Experiences
… During the summer of 2021, 13 interns from UC Merced spent eight weeks working virtually with JGI mentors to investigate rigorous research … presentation skills, and participate in professional development enrichment activities. For some students in the … Blurring the Line Between Plasmids and Phages …
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JGI@25: Cow Rumen and the Early Days of Metagenomics
… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable … process tough cell walls.  “The JGI was really leading the development of these approaches that are still vital to …
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JGI@25: From Life at the Extremes to Editing Genomes
… In honor of the JGI's 25th anniversary in 2022, we have revisited a … Such proteins have been adapted for therapeutic application development by Mammoth Biosciences, one of several companies … nature was using it to do something important.” Related Publications:  A scoutRNA Is Required for Some Type V …
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Ian Blaby
… Since 2019 Dr. Blaby heads the Biodesign Platform at the Joint Genome … and assembly, strain engineering and bioinformatic tool development/data analysis for synthetic biology and … National Laboratory where he focused on functional genomics of phototrophs. Through this and post-doctoral positions at …
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Giant Bacteria Found in Guadeloupe Mangroves Challenge Traditional Concepts
… Though visible to the naked eye, microscopy reveals unexpected complexity At first … the slightly murky waters in the tube look like a scoop of stormwater, complete with leaves, debris, and even … Moore Foundation. “We look forward to learning how the characterization of Ca. Thiomargarita magnifica challenges …
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Webinar: PhycoCosm Tutorial
… Learn more about JGI’s  PhycoCosm data portal , an interactive collection of sequenced algal genomes, omics data and comparative … on, there are 7 genomes on NCBI but your portal has only 2 of them. A: Watch the video (above) for the answer provided … related to clean energy generation and environmental characterization and cleanup. The JGI provides integrated …
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Webinar: SIP technologies at EMSL and JGI
… The Environmental Molecular Sciences Laboratory (EMSL) and the Joint Genome Institute (JGI) provide access to a variety of tools that leverage stable isotopes to measure carbon and … The more the better. We want to put at least a microgram of DNA in the tube so you’d need at least 2 micrograms in …
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