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Leo Baumgart
… his doctoral research in synthetic biology and microfluidics at the University of California, San Diego. As the Sequencing Technology … plant tissues. Dr. Baumgart focuses on expanding functional genomics capabilities through process automation and method … BS in Biochemistry and Cell Biology, University of California, San Diego PhD in Molecular Biology, …
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An Integrated Dataset to Understand Ecosystem Interaction
… data set will help identify how different elements of the ecosystem interact and respond to changes in the … their genetic diversity. They hold economic value as both biofuel feedstock and their role in carbon sequestration. … managed through human intervention. By leveraging metagenomics, scientists were able to analyze the DNA of …
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Biodesign
… automations for DNA design, assembly and analysis Overview of biodesign products The JGI Biodesign platform enables … BOOST provides a suite of tools to automate sequence design for assembly by Gibson, … Software Engineers in the Synthetic Biology Informatics Group …
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Better Genome Editing for Bioenergy
… A team has optimized a crucial part of CRISPR-Cas9 technology to enable improvements in … tool will make the right cut, researchers created a set of guide RNAs that were effective against 94 percent of the genes in a lipid-prolific yeast. The Impact The team … MB) and NSF  1706545 (IW). HA and JW were supported by the Office of Naval Research under grant  N00014-15-1-2785 . JW …
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Fields of Breeders’ Dreams: A Team Effort Toward Targeted Crop Improvements
… crop and ornamental seeds sold for the upper Midwest are often very different than those bred for Texas. Identifying … test what genes affect the plant’s adaptability to various environmental conditions. “To accelerate breeding for  … sites. “This paper is a combination of really cutting-edge genomics and genetic analysis with large scale data …
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The Expanding Universe of Methane Metabolisms in Archaea
… gas 20 times more potent than carbon dioxide. Billions of years ago, methane-producing archaea likely played a key … in April, which immediately precedes the JGI’s 14th Annual Genomics of Energy & Environment Meeting. Registration for … between methanogenesis and sulfite reduction depending on environmental conditions, or it could couple the two …
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Engagement Webinar: Harnessing JGI’s Metabolomics Capabilities
… (CSP) . This includes mass spectrometry-based measurements of primary and secondary metabolites from plants, microorganisms, and environmental samples using targeted and untargeted … analyses? A:  For the JGI  New Investigator and  Functional Genomics proposal calls, projects can request up to 50 polar …
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The Genome Portal of the Department of Energy Joint Genome Institute
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The Phaeodactylum genome reveals the evolutionary history of diatom genomes
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Katherine Louie
… efforts to expand the metabolomics capabilities and product offerings for JGI users.  Using cutting-edge mass … techniques, the platform delivers rich metabolite profiles from diverse biological and environmental samples in support of user science.  … A, et al. Anaerobic gut fungi are an untapped reservoir of natural products. Proc Natl Acad Sci U S A. 2021;118. …
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2023 Progress Report
… for a sustainable bioeconomy. Mission  As a U.S. Department of Energy Office of Science user facility, we provide advanced genomic … research community in studies of complex biological and environmental systems. We optimize our service to the …
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… from single cells. The Science Studying the  genomes of microorganisms is incredibly useful for understanding the microbiome of the earth, but most species do not grow easily in the lab. To access the genomes of uncultured  microbes , scientists usually employ two …
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