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High Five: Celebrating the JGI-UC Merced Genomics Internship Program
… than 20 UC Merced students have contributed to the research of 13 JGI scientists since the program’s inception. In 2014, … Science Programs Deputy Axel Visel teamed with University of California (UC), Merced assistant professor Suzanne Sindi … Clarissa Nobile, investigating interactions between microbes and venomous hosts. She also facilitates the …
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Busting the Unbreakable Lignin
New evidence shows anaerobic fungi can degrade the hardiest of plant components   The Science There are three main … skeleton. It’s more complex, and poisons enzymes and the  microbes that make them. It’s known that aerobic fungi, like … using magnetic fields to diagnose electronic structure and functionality on the atomic level, was generated at JBEI and …
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Len Pennacchio
Joint Genome Institute and has focused on applying state-of-the-art molecular methods to address wide-ranging … Scientist at Lawrence Berkeley Laboratory, and Adjunct Professor at UC Berkeley. Dr. Pennacchio received his Ph.D in … in both the energy and health sectors. Mammalian Functional Genomics Lab VISTA Enhancers VISTA Cardiac …
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Designer DNA: JGI Helps Users Blaze New Biosynthetic Pathways
A special issue of Synthetic Biology celebrates research enabled by the JGI … the JGI DNA synthesis Community Science Program (CSP) Functional Genomics, the system allows scientists to test … on thiolases, a superfamily of enzymes found only in microbes, which make carbon-carbon bonds. This ability is …
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Inspiring STEM Careers Through a Hands-on Everglades Microbiome Study
… school scientists. The Florida Everglades evokes images of fanboats skimming over swamps, while alligators peer through the waters and clouds of insects hover just above. Described as a “river of grass” … Everglades in Palm Beach County, and particularly about the microbes that play roles in the methane cycle. Their data …
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John Vogel
Dr. Vogel joined JGI in 2014 to establish a plant functional genomics program. Prior to this, he served as a … years where he was a driving force behind the development of numerous genomic resources that fostered the widespread … Dr. Vogel’s current research is focused on developing plant functional genomic resources (e.g. sequenced mutant …
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Jeremy Schmutz
… human chromosomes 5, 16, and 19. Following the completion of the human genome project in 2003, he developed … assembly, and improvement strategies for de novo sequencing of eukaryotic organisms from simple yeasts to large … gene atlas: an updateable transcriptome resource to improve functional gene descriptions across the plant kingdom. …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… ( CRAGE ). CRAGE enables scientists to insert large pieces of DNA (up to 60 kb) in a single step, directly into the … advantage of their joint metabolisms. Because, together, microbes can be used to create compounds more efficiently … strains as part of the Community Science Program (CSP)  Functional Genomics proposal call. …
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Streamlining Regulon Identification in Bacteria
… with their target genes. The Science Regulons are a group of genes that can be turned on or off by the same regulatory … genome science user facility, connecting genes to functions is part of the mission of the U.S. Department of … across various environments are expressed when their functions are needed. Data yielded through RIViT-seq expand …
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Nikos Kyrpides
… 2004 to lead the Genome Biology Program and the development of the comparative analysis platforms for microbial genomes … Joint Genome Institute, Dr. Kyrpides led the development of the genome analysis and Bioinformatics core at Integrated … Crete, Greece … Pavlopoulos GA et al. (2023) Unraveling the functional dark matter through global metagenomics. Nature . …
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JGI@25 RECAP: 2022 Annual Meeting features historical perspectives on JGI’s 25 years
As part of the JGI’s 25th anniversary celebration, the 2022 Annual … sequencing for the Human Genome Project out to the future of the institution. Their talks shed light on how the JGI … currently works to support understanding of plants, microbes and environmental communities that have relevance …
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Evolution of a Fungal Gene Expression Regulator
Describing the largest analysis to date of the modified DNA base 5mC variations in fungi. The … sequence can lead to changes in protein structures and functions, but the DNA bases themselves can also be modified. The best-known example of a modified DNA base is a methylation of the base cytosine …
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