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For years, extracting single cells and then amplifying their DNA for genome sequencing was no easy task. The traditional way of collecting them is through a method called … Primary Template-Directed Amplification (PTA) yields a much higher completion, above 80% in most cases. The Impact …

DNA genomes that co-infect eukaryotic cells along with giant viruses. Virophages are small viruses with … the US Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science facility, have increased the … 89 contigs were considered to be complete genomes, and their discovery has extended the possible virophage genome …

Ph.D. in Computer Science. Her research has been focused on semantic and object-oriented data modeling, and … at the JGI, responsible for the data management infrastructure of the Integrated Microbial Genomes (IMG) family of … data, one of the most successful data management systems of their kind, deployed to tens of pharmaceutical and biotech …

… team  announced in  Nature Microbiology an important addition to the synthetic biologist’s toolkit: a technique for  c … versatile engineering system that allows scientists to conduct genome-wide screens and explore biosynthetic pathway. … and ecosystem health. But bacteria often fail to express their BGC molecules in the lab. By engineering domesticated …

Dr. Udwary serves as a computational biologist for JGI’s Secondary Metabolites group. His research interests … lie in use and development of bioinformatics tools for elucidation of biosynthetic gene clusters in bacteria and …

… tools for comparative genomics and community annotation. Presented by Igor Grigoriev, Steven Mondo, Steven Ahrendt and Sajeet Haridas. …

To boost crops more efficiently in the future, the evolutionary past may hold key insights. The way that plants … leaving potential targets for crop engineering untouched. Research recently published in  The Proceedings of … 25, and eukaryotes having slightly larger numbers due to their expanded metabolisms. These ATs can operate in a …

… single-cell genomic approach to bioprospecting. The Science One of the most vital pieces of equipment for fly fishing is … ecosystem—particularly those that are in low abundances—and their functional roles in their community. This study shows … the researchers also hooked and were able to reconstruct a high-quality draft co-assembled genome for a new genus …

… biosynthetic gene clusters.  The Science Microbial secondary metabolites, those molecules not essential for growth … CRISPR provides researchers with a powerful addition to their toolkit to study gene function. As a demonstration, … the functions of the biosynthetic gene clusters that produce them. The Impact Secondary metabolites are microbial …

… expands inovirus diversity. To answer the question, “Where’s Waldo?” readers need to look for a number of … developed an algorithm that a computer could use to conduct a similar type of search in microbial and metagenomic … without lysing the bacterial host. They can also influence their host’s growth and pathogenicity, in turn affecting the …

… a microbiome of bacteria, viruses and fungi process carbon and nitrogen, paving the way for future plants and trees … it was possible to identify specific attributes — such as heat resistance, fast growth rates, and an ability to … and growth.  This study builds on the pyrophilous fungi the JGI has previously sequenced , and provides a powerful …