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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… A group led by JGI scientists have made strides in improving and applying a method that allows researchers … be engineered. “Piloting access to this emerging technology with JGI users will enable us to assess CRAGE’s impact, … “Once you have a landing pad in a strain, you can deliver multiple types of payloads, such as individual genes, whole …
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Marchantia Pangenome Highlights Adaptive Nature of Plant Lineages
… Understanding the shared genetic toolkit of ancestral and … a resource that associates plant’s genetic variants with specific adaptation mechanisms they had identified. For … Office of Science of the US Department of Energy operated under contract no. DE-AC02-05CH11231. This project received …
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Extracting the Secrets of Secondary Metabolites
… for survival, may now be easier to characterize following a proof-of-concept study in which researchers paired … payloads directly into diverse microbes. Combining CRAGE with CRISPR provides researchers with a powerful addition to … into the insect’s bloodstream that quickly kill the host. Understanding exactly how P. luminescens and its secondary …
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Supercharging SIP in the Fungal Hyphosphere
… High-throughput stable isotope probing helps ID novel interactions between bacteria and fungi … a commonly-used process for studying microbial communities, with results published in the  November 2022 issue … carbon and mitigating greenhouse gas emissions, and understanding how to improve soil health can help mitigate …
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Four Researchers Join JGI User Executive Committee
… Four researchers have been elected to the User Executive Committee of the Joint Genome Institute, a Department of Energy user facility … He studies fungal biodiversity, ecology, and evolution, with a focus on microbiome sciences and fungal symbioses. He …
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Fishing for Novel Cellulose Degraders
… A “bait and hook” single-cell genomic approach to … of equipment for fly fishing is a boxful of lures. Designed with feathers or wires to mimic an insect or a particular … Using a single-cell screen, they can now identify microbes with specific functional characteristics. When they tested …
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Training the Next Generation of Talent
… New Graduate Internship Program Builds Bridges Between DOE JGI, UC Merced … student in the Quantitative Systems Biology (QSB) Group under the School of Natural Sciences (SNS). During his eight … JGI researcher, Zhong Wang, have adjunct faculty positions with the SNS, and Wang’s group was hosting another QSB …
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Nikos Kyrpides
… Dr. Kyrpides joined the DOE Joint Genome Institute in 2004 to lead the Genome Biology Program and the development of the … Inc. in Chicago, IL. He did his postdoctoral studies with Carl Woese at the University of Illinois at … BA in Biology, Aristotle University of Thessaloniki, Greece PhD …
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Better Genome Editing for Bioenergy
… A team has optimized a crucial part of CRISPR-Cas9 technology to enable improvements in microbial oil production. The Science CRISPR-Cas9 is a … of researchers sought to disrupt every gene in the genome with CRISPR-Cas9 in order to interrogate each one’s … HA and JW were supported by the Office of Naval Research under grant  N00014-15-1-2785 . JW acknowledges additional …
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Building Wet and Dry Lab Skills
… the second year of Alabama A&M University students coming to the DOE Joint Genome Institute for research and … training grant.  Building off the previous year’s project, undergraduate interns Tamyra Long and Zyiah Mikes worked with mentors Yi Zhai and John Vogel from the Plant …
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2025 NeLLi Symposium
…   Registration has closed   Registration fees: Regular attendees  (LBNL and external): $400  Industry: $450  Students and postdocs (including LBNL students and postdocs): $250      Hosted by … diversity cataloged and taxonomically classified to date. Under the “sequence to function’ umbrella, this symposium …
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Nigel Mouncey
… Dr. Mouncey joined the DOE Joint Genome Institute in 2017 as the fourth Director in its 27-year history. He has a … a long-standing interest in microbial genetics that started with his education and carried forward into his roles as a … to learn more about the program's areas of focus, major initiatives and more.  …
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