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Training the Next Generation of Talent
… DOE JGI, UC Merced Days after presenting the results of his summer research at the U.S. Department of Energy Joint Genome Institute (DOE JGI), a DOE Office of Science user facility, Keedrian Olmstead was back …
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Boosting Small Molecule Production in Super “Soup”
… Yeast strains engineered for the biochemical conversion of glucose to value-added products are limited in chemical … an alternative format for chemical synthesis in the absence of cell growth by isolating the soluble components of lysed cells. By separating the production of enzymes …
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JGI@25: Cow Rumen and the Early Days of Metagenomics
… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and … energy and environmental challenges. Oh, the magical world of the cow stomach. Rumen – and its microbes – are really a …
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A Model System for Perennial Grasses
… Panicum hallii genomes offer insights to drought tolerance. The Science Researchers … feedstock with a complex genome with multiple copies of its chromosomes. Switchgrass has deep roots that allow it to access nutrients easily from a variety of soils and has a high tolerance of extreme water …
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You Can Move, But You Can’t Hide
… to replicate themselves and spread from cell to cell. Two of the most common forms of MGEs are viruses and plasmids. They can be found in virtually all of Earth’s ecosystems. A software tool  recently described … The U.S. Department of Energy Joint Genome Institute …
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Honey Bee Gut Microbiota Divvy Up Dinner
… Scientists find bee gut microbes have a division of labor when it comes to metabolizing complex … Honey bees are invaluable pollinators — cupids of the plant world facilitating the remixing of genes in the next generation of flowering vegetation. In … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …
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Accelerating Metagenomics Discoveries with Deep Learning
… insights from metagenomic data. In deep learning, a branch of machine learning, data is passed through algorithms … into multiple interconnected layers. The architecture of these algorithms, inspired by communication networks … found in nature, allows machines to “learn” features. State of the art algorithms can perform astonishing degrees of …
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Sequencing Sphagnum Leads to Discovery of Sex Chromosomes
… A nuanced understanding of peat moss drives insight into carbon storage   The Science Boggy peatlands, which hold much of the Earth’s carbon as well as material that can be converted to energy, are made up heavily of sphagnum mosses.  New research identifies sex chromosomes …
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Viruses Reprogram Cells into Different Virocells
… from The Ohio State University and the University of Michigan studying how virus infections cause significant … metabolic changes they’ve undergone. The Impact The number of microbes in, on, and around the planet is an astronomical … viruses outnumber surface microbes 10 to 1, and 20% to 40% of the microbes are infected at any given time. Microbial …
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Engagement Webinar: How to Successfully Apply for a CSP Proposal
… and relevance to the DOE’s mission.  Have someone proofread your proposal to make sure the goals, experimental … the 500-gigabase cap and that you don’t request outside of the sample range that’s listed. Q: What are the pros and cons of proposing a truly exploratory small proposal that might …
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A Natural Mechanism Can Turbocharge Viral Evolution
… Understanding how a fundamental mechanism of evolution allows microbes to adapt to changing … cell’s membrane. Two decades ago, a team discovered a group of viruses that had in their genomes a surprising tool: a … questions, a team led by scientists at the US Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office …
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How to Target a Microbial Needle within a Community Haystack
… A workflow for capturing the genetic make-up of specific uncultivated microbes from complex environmental … deployed a pipeline to first target cells from communities of uncultivated microbes, and then efficiently retrieve and … great strides in generating genome sequences for members of the microbial world through bulk community sequencing …
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