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Better Genome Editing for Bioenergy
… A team has optimized a crucial part of CRISPR-Cas9 technology to enable improvements in microbial oil production. The Science CRISPR-Cas9 is a powerful, high-throughput … I will spend the first four sharpening the axe.” In this study,  published in  Metabolic Engineering , a team of …
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JGI Workshop at SIMB NP Meeting
… Jan. 7: New Capabilities to Study Secondary Metabolism   Although there are still a large number of secondary metabolites yet to be discovered and their …
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Whole metagenome sequencing and 16S rRNA gene amplicon analyses reveal the complex microbiome responsible for the success of enhanced in-situ reductive dechlorination (ERD) of a tetrachloroethene-contaminated Superfund site
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The Megadata of Lake Mendota - Part 2: Souped Up Computing
… This series is the story of a giant metagenome assembly from Wisconsin’s Lake Mendota. In this episode: a look at the … with the assembler program MetaHipMer2. Oak Ridge National Lab is home to two supercomputers — Summit and Frontier …
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Annual Genomics of Energy & Environment Meeting
… Genome Institute (JGI) Annual Genomics of Energy & Environment Meeting! The JGI convenes this annual gathering of leaders from diverse … sequencing, synthesis, metabolomics, data analysis, and new technology developments – that the JGI offers through …
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Examples: Successful LOIs & Submissions
… Program Large-Scale Call, as well as successful submissions to our CSP New Investigator, CSP Functional Genomics, and Facilities Integrating Collaborations for User Science calls. These documents have been shared … Elucidating Sphagnum microbiome genetic interactions for improved growth at elevated temperatures …
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Adam Reisselman on being a 2016 DOE Computational Science Graduate Fellow
… The Department of Energy's Computational Science Graduate Fellowship (DOE CSGF) program was developed to meet the Nation's growing need for science and technology professionals with advanced computer skills. …
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Marine Microbe Contains Multitudes
… A deep dive into microbial genomics reveals one bacterial species is made of four ecologically distinct … SAR324 exist in so many varied environments? Now, a recent study published in Microbiome has uncovered that SAR324 … sequenced community genomes and expressed gene transcripts (metagenomes, metatranscriptomes), as well as the genomes of …
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Leo Baumgart
… the University of California, San Diego. As the Sequencing Technology Implementation Lead, he directs a multidisciplinary team responsible for piloting and operationalizing new genomic … training in bioinformatics, Lawrence Berkeley National Lab … Baumgart, Leo A., Sharon I. Greenblum, Abraham Morales-Cruz, Peng Wang, Yu Zhang, …
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Partnering with CalTeach – Training the Next Generation STEM Workforce
… As set out in the JGI Five-Year Strategic Plan – “Beyond Basepairs, A Vision for Integrative and  Collaborative Genome Science” – … JGI, we seek to inspire more students to enter the science, technology, engineering, and mathematics (STEM) workforce. …
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An Automated Tool for Assessing Virus Data Quality
… Through advances in sequencing technologies and computational approaches, more and more virus sequences are being recovered and identified from environmental samples (metagenomes). However, the quality and completeness of … The work was led by research scientist Stephen Nayfach, the study’s first author in the Microbiome Data Science group …
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A Plantiful Future: Xiaohan Yang
… a renewable energy future? Can they help lock away more carbon? Xiaohan Yang, a scientist at Oak Ridge National Laboratory, believes they can. And, what’s more, that using gene editing technology to conscientiously mix traits of different plant …
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