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Yasuo Yoshikuni
… et al., CRISPR-CRAGE enables rapid activation of secondary metabolite biosynthetic gene clusters in bacteria, Cell Chemical Biology , 2022 …
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Back in the Lab: the 2023 Summer Intern Experience
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Leo Baumgart
… to a wide range of JGI user science projects spanning bacteria, fungi, and plants. His team is also developing … Matthew J. Blow et al. "Persistence and plasticity in bacterial gene regulation." Nature methods 18, no. 12 (2021): 1499-1505. Hasty, Jeff, Leo Alexander Baumgart, Scott …
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Designer DNA: JGI Helps Users Blaze New Biosynthetic Pathways
… understand a special class of compounds, or secondary metabolites, called terpenes. Terpenes are made via a … through the JGI DNA synthesis Community Science Program (CSP) Functional Genomics, the system allows scientists to … Institute of Aquatic Science and Technology in September 2021. Robinson stressed that the DNA Synthesis Science …
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Workforce Development & Education Outreach
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Ian Blaby
… worked with a wide range of eukaryotic algae, archaea and bacteria with a view to developing a deeper understanding of … site ties heme availability to carbon metabolism in cyanobacteria Nature Communications 15(1) 3167. 2024 Simirenko et … in Bioengineering and Biotechnology. 11. 2023 Liu et. al., Bacterial genome editing by coupling Cre-lox and CRISPR-Cas9 …
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JGI@25: Building a Better Bean
… shelf-life — up to four years. Work is now underway to transfer the trait into other classes of common beans. …
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Nikos Kyrpides
… bacteriophages. Cell . 185(21):4023-4037 Nayfach S, et al. (2021) Metagenomic compendium of 189,680 DNA viruses from the … Nat Microbiol . 6(7):960-970. Nayfach S, et al. (2021) CheckV assesses the quality and completeness of … Roux S. et al. 2019. Cryptic inoviruses are pervasive in bacteria and archaea across Earth’s biomes. Nature …
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Refining the Process of Identifying Algae Biotechnology Candidates
… strain to find out how well it performed under varying temperature conditions. The Scenedesmus genome was sequenced …
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Exploring Possibilities: 2022 JGI-UC Merced Interns
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Uncovering Novel Genomes from Earth’s Microbiomes
… of biosynthetic gene clusters for novel secondary metabolites for multiple applications. Despite advances in … samples around the world, expanding the known diversity of bacteria and archaea by 44%, is now available and  described … more.) One group mined the dataset for novel secondary metabolites of secondary metabolite biosynthetic gene …
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JGI@25: The Human Genome Project, or the JGI’s Origin Story
… weapons stockpile and was interested in investigating the effects of radiation exposure to human health. Three DOE …
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