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Doubling Down on Known Protein Families
… Using a novel computational approach, researchers confirm … online Oct. 11, 2023 in  Nature highlights the vast array of functional diversity of microbes through a novel approach to better understand … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …
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Bacteria and Fungi Divvy Up the Work in Forest Floor
… analyzing the enzymes present in the complex organic matrix of the forest floor, a team of researchers have found that there is a striking division … role that fungi can’t fulfill by fixing nitrogen and using it as an energy source. No fungi are known to be able …
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For the Tiniest Archaea, A Genomic Switch of Friend or Foe
… The Science Within the archaeal domain, there is a group of tiny hitchhikers. These organisms are abundant and yet … mini genomes to match. As a result, they cannot process all of the chemicals they need to survive. To fill in their … confirm the microorganisms had a close relationship. Then, using metagenomes and metatranscriptomes generated by the …
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Optimized CRISPR Interference System for Investigating Pseudomonas alloputida Genes Involved in Rhizosphere Microbiome Assembly
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Fishing for Novel Cellulose Degraders
… genomic approach to bioprospecting. The Science One of the most vital pieces of equipment for fly fishing is a boxful of lures. Designed … at Lawrence Berkeley National Laboratory (Berkeley Lab). Using a single-cell screen, they can now identify microbes … The work conducted by the U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …
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Data Ecosystem
… The JGI is leveraging its current partnerships to offer new capabilities and resources to users through a BER … is discoverable and accessible. Linking the resources of powerful institutions like the JGI, KBase, NCBI, NMDC, … access to diverse datasets that deepen our understanding of how organisms interact with each other and with their …
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Jane Grimwood Named HudsonAlpha Genomics Chair
… Biotechnology! Loretta Spencer served as a manyterm mayor of Huntsville, Alabama and is known for her contributions to … large-scale multi-institutional JGI projects and resulting publications that Grimwood contributed to include: A 2021 … reference sequence of the complex switchgrass genome , using samples from common gardens growing across the …
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Gut Fungi: Unexpected Source of Novel Chemicals
… The Science Anaerobic fungi, which die in the presence of oxygen, dwell in herbivore guts and help them digest … meal. In their evolutionary history, these fungi branched off early from aerobic fungi, which can breathe oxygen — … source of antibiotics. Indeed, these anaerobic fungi may be using these compounds for self-defense. But the compounds …
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You Can Move, But You Can’t Hide
… to replicate themselves and spread from cell to cell. Two of the most common forms of MGEs are viruses and plasmids. They can be found in … and metatranscriptomes. To lower barriers to accessing and using geNomad, the JGI partnered with the NMDC to integrate … The U.S. Department of Energy Joint Genome Institute …
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Understanding Wildfire Recovery, Starting in Soil
… begins at the forest floor. Within the soil, a microbiome of bacteria, viruses and fungi process carbon and nitrogen, … the microbes within the soil. To get a clearer picture of how burned ecosystems return to health, researchers have … published in Nature Microbiology , went a step further, using both DNA and messenger RNA (mRNA) sequencing to …
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Silver age of GOLD introduces new features
… sequencing projects carried out at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office … a broad range of activities from proposal intake to publication. Information is also obtained and cross-checked … the past, GOLD relied on free text fields, it now leverages controlled vocabularies with unit-based fields like depth …
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A Natural Mechanism Can Turbocharge Viral Evolution
… Understanding how a fundamental mechanism of evolution allows microbes to adapt to changing … For a virus with a “head-tail” morphology, this means using proteins on its tail fibers to latch onto a specific … cell’s membrane. Two decades ago, a team discovered a group of viruses that had in their genomes a surprising tool: a …
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