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iPHoP: A Matchmaker for Phages and their Hosts
… computation helps fill in what cultivation can’t. The Science At first, viruses are merely toolkits. To do … nutrient cycling, or carbon sequestration. Summary Existing programs use a variety of approaches to match a virus with a … of Energy Joint Genome Institute, a DOE Office of Science User Facility at Lawrence Berkeley National …
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Plotting a Model for Virus-Host Warfare Deep Below Ground
… viral genome found in the deep subsurface ecosystem. The Science Altiarchaea are carbon-fixing microbes and targets … by combining a study of microbial communities (metagenomics) and a chemical labelling approach. The Impact … releasing fresh organic carbon which can serve as a food source for other microbes into the environment. Summary In J. …
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GenomeOcean Leverages AI to Decode Nature’s Secret Language
… genetic blueprint has long been a significant challenge in genomics. Enter GenomeOcean, a powerful generative model  … Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National … the human language—are well positioned to help enhance our understanding of life’s genomic code, advancing DOE …
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A Redesign for Yeast’s Genome, Chromosome by Chromosome
… To engineer yeast to do more, and understand genomes in general, Jef Boeke, Weimin Zhang (NYU Langone … yeast’s native chromosomes with synthetic versions. This project has turned out to be an international collaboration, …
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Busting the Unbreakable Lignin
… fungi can degrade the hardiest of plant components   The Science There are three main ingredients to tackle when it … yield fuels, and removing lignin in order to do so is a resource-intensive process. Now, a new study shows how … conducted RNA sequencing and alignment to the reference fungal  genome . The study’s pivotal NMR (nuclear magnetic …
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User Executive Committee
… on JGI policies and practices that affect users and their science including technical capabilities offered, proposal …
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Iron-rich Microbial Mats’ Main Players: Marsarchaeota
… may have been important in early Earth conditions. The Science Through a combination of sequencing tools and … and direct microscopy. Through the JGI’s Community Science Program , the team used metagenome assemblies, transcriptomes and single amplified genomes from samples collected from several locations to …
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Nigel Mouncey
… joined the DOE Joint Genome Institute in 2017 as the fourth Director in its 27-year history. He has a wealth of … and Bioprocessing R&D Director and Leader at Dow AgroSciences in Indianapolis. During his time in industry, Dr. … to build and position JGI as a leading integrative genome science user facility.  In addition to serving as JGI …
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Access to Rock Star Scientists
… Through the JGI-UC Merced Genomics Internship, graduate students Candace Cole, Mo … the big stuff, well, the little stuff! People hold office hours and you can pop in and ask them questions about all … Wint, UC Merced JGI Mentors: Igor Grigoriev & Asaf Salamov, Fungal Program “Working at the JGI has reinforced my plans …
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Engagement Webinar: Utilizing long-read sequencing for metagenomics and DNA modification detection
… genome assembly and transcriptome analysis of microbial, fungal, and plant research projects.  More recently, these … weight DNA) is an important factor as well for PacBio metagenomes. Q: How many PacBio metagenomes can I submit?  How … PacBio reads (i.e., reads with very low error rate), so our pipeline performs long-reads-only assemblies and not …
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Mining Metagenomes for Cas Proteins
… characterized at UC Berkeley and the Innovative Genomics Institute.  The Science Researchers report the discovery of miniature … of thermostable Cas9 genes . The work also used resources at the National Energy Research Scientific Computing … of Energy Joint Genome Institute, a DOE Office of Science User Facility, is supported by the Office of Science …
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Informatics Advisory Committee
… management and strategic objectives for the JGI’s data science, informatics and information technology (IT) …
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