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New Vision, New Mission, New Plan: The JGI’s Next Five Years
… Department of Energy (DOE) Joint Genome Institute (JGI) has released its newest 5-Year Strategic Plan: Innovating Genomics … gaps to advance biotechnology and biomanufacturing.  As a leader in genomics for bioenergy and environmental …
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iPHoP: A Matchmaker for Phages and their Hosts
… any host will do. It must be a specific host the virus has adapted to commandeer. For bacteriophage viruses, these … to 216,015 high-quality virus sequences in the IMG/VR database, the iPHoP program generated many new high-confidence … microbiome data. In other environments, such as terrestrial soil, having additional isolates and metagenomic datasets …
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Hiroshi Otani
… joining the DOE Joint Genome Institute in 2016, Dr. Otani has been studying secondary metabolism in microbes, … BS, Engineering, Tokyo Institute of Technology Master's, Biotechnology, University of Tokyo PhD, … Characterization of p-hydroxycinnamate catabolism in a soil Actinobacterium. J. Bacteriol. 196, 4293-4303. Otani, …
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Uncovering Novel Genomes from Earth’s Microbiomes
… sequencing technologies and computational methods in the past decade, researchers have uncovered genomes for just a … archaea by 44%, is now available and  described November 9, 2020 in  Nature Biotechnology . Known as the GEM (Genomes … and environments, including natural and agricultural soils, human- and animal-host associated, and ocean and …
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Yasuo Yoshikuni
… Dr. Yasuo Yoshikuni has been head of the DNA Synthesis Science Program since … discovery and applications. This program has supported over 250 projects since it started. At the JGI, … His research focus includes engineering of non-model yeasts for production of biofuels and renewable chemicals, …
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Dan Rokhsar
… Dr. Rokhsar joined the JGI in 2000 as the founding Associate Director for Computational Genomics, and led the … of the Human Genome Project, Professor Dr. Rokhsar ’s team has continued to develop computational methods applicable to …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… modify diverse bacterial genomes. In 2019, the JGI’s Yasuo Yoshikuni and his team  announced in  Nature … to the synthetic biologist’s toolkit: a technique for  c hassis (or strain)-independent  r ecombinase- a ssisted  g … bacterial strains as part of the Community Science Program (CSP)  Functional Genomics proposal call. …
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Igor Grigoriev
… in the pharmaceutical industry. He holds joint appointments as Fungal and Algal Program Head at the JGI, a Senior … Head at the JGI. Click to learn more about the program's areas of focus, major initiatives and more.  … Natl Acad Sci U S A. 118(18):e2019855118. Miyauchi et al (2020) Large-scale genome sequencing of mycorrhizal fungi …
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Here, There and Everywhere: Large and Giant Viruses Abound Globally
… population, the number of viruses in the same drop—the vast majority not harmful to humans could be even larger. … viruses are on the order of 100 times the size of what has typically been associated with viruses, while the genomes … study from a JGI-led team uncovered giant viruses in the soil for the first time. The current study applied a …
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Changes to virus taxonomy, the international code of virus classification and nomenclature, and the ICTV statutes ratified by the International Committee on Taxonomy of Viruses (2025)
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An Addiction Crucial to a Fungus’ Reproduction
… The bacterial endosymbiont, Burkholderia , is recognized as a mutualist, where both species of organism benefit from association, but was predicted to have evolved from a parasitic interaction with their soil fungus host, Rhizopus microsporus . Researchers found …
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Dealing with Drought: Uncovering Sorghum’s Secrets
… in many regions due to more extreme weather events such as heat waves, droughts and floods. The planet’s resources … grass that adroitly handles droughts, floods and poor soils. This is the first paper that describes sorghum’s … conditions, and then collected root, leaf and rhizosphere (soil surrounding the root) samples from the plants at the …
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