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For the Tiniest Archaea, A Genomic Switch of Friend or Foe
… Meta-omics datasets show that CRISPR-Cas systems determine mutualism or parasitism … they need to survive. To fill in their nutrient gaps, they must latch onto a larger host — often, a fellow archaeal … cycling across the planet. Summary To understand more about how archaeal hosts and hitchhikers coexist, …
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Streamlining Regulon Identification in Bacteria
… technology could speed up associating transcription factors with their target genes. The Science Regulons are a group of … sigma factors that initiate transcription in bacteria. Using this technology, which combines an in vitro … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at …
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Green Algae Reveal One mRNA Encodes Many Proteins
… Gene expression in eukaryotes was long held to be monocistronic – that is, a single gene … messenger RNA, which encodes a single protein. Recently reported in the Proceedings of the National Academy of Sciences , a team of researchers has found numerous examples of polycistronic expression – in which two or …
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Plant Microbial Interactions Group
… detrimental microbial pathogens, and associated viruses that all contribute to a dynamic ecosystem. We are interested in how plants self-organize, influence, and are influenced by microbial partners. We use a variety of genomics-powered tools to study this …
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Sequence to Function: Applications and Analysis for the Future (SFA²F)
… established and emerging scientists from academia, industry, and government organizations for three days of scientific presentation, interactive panel discussions, workshops, and informal networking events. JGI will present … center talk and a tech talk. Stop by the JGI booth to learn about our user programs and how we can help advance your …
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Cultivating Symbiotic Antarctic Microbes
… Impact The Antarctic lakes are a “treasure trove” of unknown microbes that play critical roles in environmental … ecological consequences of microbe-microbe interactions. Using metagenomes recovered directly from environmental … researchers have been able to gain further insights about how microbes have adapted to thrive in polar …
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How to Target a Microbial Needle within a Community Haystack
… A workflow for capturing the genetic make-up of specific … targeted genomic approach would allow researchers to focus on specific microbes within metagenome samples and … traditional shotgun metagenomics approach to learning more about environmental samples starts with researchers first …
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Igor Grigoriev
… Dr. Grigoriev joined the JGI in 2003, following his postdoctoral training at UC Berkeley and work in the pharmaceutical industry. He holds joint appointments as Fungal and Algal … Algal Science Program Head at the JGI. Click to learn more about the program's areas of focus, major initiatives and …
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Bacterial response to the 2021 Orange County, California, oil spill was episodic but subtle relative to natural fluctuations.
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An Enzyme Family that Helped Shape Nitrogen Metabolism on Our Planet
… enzyme family evolved across 90 species. “One unique thing about this work was our focus on all the kingdoms, including animals, plants, bacteria, … nitrogen metabolisms can be so varied.  As evolution has progressed, organisms have developed metabolisms that …
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The More the Merrier: Making the Case for Plant Pan-genomes
… system traces polyploid genome evolution. Flowering plants abide by the concept, “the more the merrier,” … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National … of Energy Joint Genome Institute, a DOE Office of Science User Facility  located at Lawrence Berkeley National …
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Notes on the Microbial Diversity of Puerto Nuevo’s Coastline
… Puerto Nuevo is a small town along the Baja California coastline in Mexico. While … snails, UC Merced graduate student Sabah Ul-Hasan and alumnus of the JGI-UC Merced Genomics Internship Program, first … Nuevo is, historically, a fishing town and we know little about its coastal microbial ecology. We also know little …
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