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DAP-seq Drives Robust Mapping of Gene Regulation
… deciphering the complex wiring behind a city’s power grid. Just as the flow of electricity controls when and where … genes are activated to sustain life’s processes.  Traditionally, mapping this intricate network of regulatory … from grasses to broccoli and trees like poplar, spanning about 150 million years of evolution,” said Leo Baumgart, …
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JGIota: The Algae Nicknamed ‘Chlamy’
… This shorter episode is about a tiny, single-celled alga – Chlamydomonas reinhardtii – that’s managed to have a big impact. UC Berkeley plant … managed to sequence its genome, and what it has to teach us about other organisms – like plants. [ Editor’s Note: …
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Boosting Small Molecule Production in Super “Soup”
… Rasor) Think of cells as tiny factories: within their walls they have both the machinery to make products such as … to keep processes running smoothly. As  reported August 26, 2021, in  Nature Communications , researchers led by … and so one of the things that I think is so special about this collaboration is that we’re doing work in yeast, …
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Informatics Advisory Committee
… The IAC is chartered by the JGI Chief Informatics Officer (CIO) and reports to the JGI Director. The IAC is chartered to render advice, …
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Gut Fungi: Unexpected Source of Novel Chemicals
… poop make surprisingly complex compounds — an energetically expensive feat thought to be too costly for them. The … off early from aerobic fungi, which can breathe oxygen — just like we do. Oxygen is a rich source of energy, and … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at …
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A Sorghum Pangenome Opens More Doors to Discovery
… development, dozens of reference genomes and thousands of resequenced sorghum varieties, a resource for … bolstering sorghum fields, understanding this plant eventually offers avenues for translating its strengths into other … how we think of things that we thought we knew everything about,” said Lovell.  In future work, a pangenome offers …
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Marchantia Pangenome Highlights Adaptive Nature of Plant Lineages
… Science In a recent  Nature Genetics paper , researchers focused on the full composition of genes, or pangenome, of the … that certain gene families — including fungal genes horizontally transferred — contributed to the ecological resistance … Summary As the planet has changed, so have plants. Curious about their ability to adapt to changing environments, …
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Streamlining Regulon Identification in Bacteria
… sigma factors that initiate transcription in bacteria. Using this technology, which combines an in vitro … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … of a core enzyme complex as well as a sigma factor. While all bacteria encode at least one principal sigma factor …
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Cultivating Symbiotic Antarctic Microbes
… multiple microbiology and ‘omics techniques to experimentally determine that Nanohaloarchaeota are symbionts, rather … ecological consequences of microbe-microbe interactions. Using metagenomes recovered directly from environmental … researchers have been able to gain further insights about how microbes have adapted to thrive in polar …
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Notes on the Microbial Diversity of Puerto Nuevo’s Coastline
… Puerto Nuevo is a small town along the Baja California coastline in Mexico. … snails, UC Merced graduate student Sabah Ul-Hasan and alumnus of the JGI-UC Merced Genomics Internship Program, first … Nuevo is, historically, a fishing town and we know little about its coastal microbial ecology. We also know little …
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Yasuo Yoshikuni
… has supported over 250 projects since it started. At the JGI, Dr. Yoshikuni also manages the Synthetic Biology Pathway Engineering group. His research focus includes engineering of non-model yeasts for production … unlocking the potential of macroalgae as an environmentally sustainable and cost-effective biomass for production …
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Accelerating Metagenomics Discoveries with Deep Learning
… how researchers are utilizing deep learning to automatically generate insights from metagenomic data. In deep … workshop, Volkan Sevim, a computational biologist at the US Department of Energy (DOE) Joint Genome Institute (JGI), presented on generating vector representations of …
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