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A Pinch of Salt Activates Silent Gene Clusters in Streptomyces
… This single environmental trigger highlights efficiency for users requiring multiple omics methods to examine microbial chemical production. The Science Soil bacteria in the genus … nature's chemical factories. They hold genetic blueprints for dozens of complex compounds, but stay largely dormant …
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Microbial Program
… inter-organismal interactions. These insights are crucial for addressing key environmental challenges, such as … and inter-organismal interactions, which are critical for advancing sustainable solutions in agriculture, energy … to generate high-quality genomic datasets, particularly for uncultivated microorganisms, by sequencing large …
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Calculating the Costs of Multiple Switchgrass Gene Copies
… of Texas (UT) at Austin, the HudsonAlpha Institute for Biotechnology (HudsonAlpha), and the U.S. Department of … natural sampling and field experiments due to its potential for habitat restoration and as a feedstock for biomass-based biofuel production. As seen with many commonly cultivated commercial …
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Triggering Morel Fruiting
… Fungal Genomes Project, which aims to provide genomic information for every family of fungi. In the following guest piece, JGI user Dr. Tan … are economically, culturally, and ecologically important fungi, widely prized as a culinary delicacy, but also … address some of the most pressing challenges of our time. For more information, please visit  …
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Corymbia Genome Expands Terpene Synthesis Knowledge
… Australia but is increasingly farmed in other countries for essential oil production. The recent assembly of two Corymbia citriodora … the conservation and evolution of the genes responsible for terpene synthase (TPS) enzyme production. This family of … was supported by FAPDF grant “Nextree” 193.000.570/2009. For the portion of the work conducted by the Joint Genome …
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JGI Announces 2023 Community Science Program Awardees
… to the proposers of the 19 proposals selected for the 2023 Community Science Program call of the U.S. … questions relevant to the DOE mission, and we look forward to facilitating their success. “ The CSP Annual Call … (BER) missions in: sustainable biofuel and bioproducts production, global carbon and nutrient cycling, and …
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2024 Progress Report
… also co-located in the IGB. Vision  Lead genomic innovation for a sustainable bioeconomy. Mission  As a U.S. Department … to realize our new vision to, “ Lead genomic innovation for a sustainable bioeconomy ” — as articulated in our new … transcriptomics, and cell- and cell-free expression platforms.  …
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Dealing with Drought: Uncovering Sorghum’s Secrets
… by a growing human population and increasing demand for agricultural products.  Sorghum bicolor (L.) Moench is … this to be a candidate bioenergy crop for its potential production of biomass on marginal lands not usable for … relationship between plant roots and arbuscular mycorrhizal fungi (AMF), known to provide plants with nutrients and …
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JGI@25: Cow Rumen and the Early Days of Metagenomics
… the ability to break down hardy plant cell walls and therefore hold clues to how humans could do the same on an … study subject that could lead to more sustainable energy production.  However, less than 10% of the microbes found in … head of the Hess Lab at UC Davis. “It was a really huge effort in tool development and … that was really the …
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Mining Public Databases Yields Largest Map of Fungal Mitochondrial Genomes to Date
… fungal mitochondrial genome data, unlocking new potential for AI-driven studies of energy metabolism. The Science … The team identified 15 core genes shared across all fungi, and found that some of these genes have moved from … this set, the same 15 core genes — 14 encoding energy-production proteins plus one ribosomal protein gene — were …
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DOE Metrics
…     2,208     *Includes Illumina and PacBio sequencing platforms. **Operating Hours target is based on 98% of the total … 2,208 102.0% *Includes Illumina and PacBio sequencing platforms. **Operating Hours target is based on 98% of the total … System (LIMS) and temporary shut down of the sequencing production line to accommodate data migration requirements. …
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Complete Genome of Oil-Rich Alga Reveals Ideal Platform for Bioengineering
… Streamlined genome with precise gene targeting transforms oil-producing alga into a powerful platform for developing ​​bio-based industrial products.    The … modeling and pathway optimization for enhanced lipid production. Also notable, researchers found it is missing 33 …
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