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Genomes from uncultivated bacteria offers clues to ancestral … postdoctoral fellow Paula Matheus Carnevali was working with a group of metagenome-assembled genomes (MAGs) dubbed … and computational analysis that enable systems-based scientific approaches to these challenges. DOE’s Office of …
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… and then efficiently retrieve and characterize their genomes. The Impact Despite great strides in generating … would allow researchers to focus on specific microbes within metagenome samples and associate their sequences with … users in order to address pressing energy and environmental scientific challenges. … The work conducted by the U.S. …
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… at the supercomputing that stitches together large datasets with the assembler program MetaHipMer2. Oak Ridge National … — Summit and Frontier — that process terabytes of data with MetaHipMer2. And the National Energy Research Scientific Computing (NERSC) has another supercomputer, …
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… of the JGI Progress Report highlights notable research and scientific collaborations in 2018. The cover is an image of …
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PIs have proposed research that addresses various important scientific questions relevant to the DOE’s mission, and I …
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… of researchers sought to disrupt every gene in the genome with CRISPR-Cas9 in order to interrogate each one’s … to fix a defect in the approach: CRISPR-Cas9 relies on RNA with a short guiding sequence (20 bp) that directs the … cut, but these “single guide” RNAs (sgRNAs) can be faulty. Without a good sgRNA, Cas9 is ineffective and leaves the …
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New genomes highlight the diversity of white rot fungi in the … sequences, this work expands the family tree for Lentinula. Within those samples, this study also tracks the enzymes … more genetic diversity in wild Lentinula species compared with farmed cultivars, highlighting a potential conservation …
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