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The Megadata of Lake Mendota - Part 2: Souped Up Computing
… series is the story of a giant metagenome assembly from Wisconsin’s Lake Mendota. In this episode: a look at the … with the assembler program MetaHipMer2. Oak Ridge National Lab is home to two supercomputers — Summit and Frontier … Perlmutter that works at large scale. But nearby the JGI, a cluster called Dori is also capable of running …
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Dealing with Drought: Uncovering Sorghum’s Secrets
Over 40 percent of the cereal crop’s genes respond to drought stress. The Science Fields of drooping stalks … and the U.S. Department of Energy Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … crops. For that reason, its genome was sequenced by the JGI in 2009 and it is considered to be a Flagship Plant. By …
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Effects of Polar Light Cycle on Microbial Food Web
Populations of Antarctic lake microbial communities change with the … Ace Lake were collected over a 10-year period and sent to JGI for metagenomic sequencing. A study  recently published … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at …
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Extracting the Secrets of Secondary Metabolites
… biosynthetic gene clusters.  The Science Microbial secondary metabolites, those molecules not essential for growth … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … CRISPR to knock out or activate genes, researchers at the JGI were able to monitor loss- and gain-of-function. The …
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Streamlining Regulon Identification in Bacteria
RIViT-seq technology could speed up associating transcription factors with their target genes. The Science Regulons are … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … Nature Communications on June 17 , 2022, was conducted by JGI Director Nigel Mouncey and research scientist Hiroshi …
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How to Target a Microbial Needle within a Community Haystack
… make-up of specific uncultivated microbes from complex environmental samples. The Science A team led by researchers at … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … Development of this protocol was enabled by the JGI’s  Emerging Technologies Opportunity Program . The ETOP …
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A Community Resource for Secondary Metabolite Researchers
The Secondary Metabolism Collaboratory encourages user engagement. … The U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … from isolate and metagenome data.   The SMC ( smc.jgi.doe.gov ) is designed with two main objectives. First …
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JGI-UC Merced Interns Share Their 2021 Experiences
… from UC Merced spent eight weeks working virtually with JGI mentors to investigate rigorous research projects, hone science presentation skills, and participate in … year and continue working on their research project! The JGI-UC Merced internship program was founded in 2014 with …
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An Enzyme Family that Helped Shape Nitrogen Metabolism on Our Planet
To boost crops more efficiently in the future, the evolutionary past may hold key insights. The way that plants … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … for computational analysis of the AT enzyme family, the JGI provided DNA synthesis capabilities to enable functional …
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The Power of One, Amplified
… metagenomics studies. The Science Researchers demonstrated the value of conducting large-scale single cell … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … was performed by Danielle Goudeau and Rex Malmstrom of the JGI’s Microscale Applications group . Cells were randomly …
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An Automated Tool for Assessing Virus Data Quality
Through advances in sequencing technologies and computational approaches, more and more virus sequences are being … uncultivated viruses. Following up on those guidelines, JGI researchers have now developed CheckV (pronounced … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at …
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Busting the Unbreakable Lignin
… shows anaerobic fungi can degrade the hardiest of plant components   The Science There are three main ingredients to … Research Center. O’Malley is also affiliated with JBEI. The JGI data portals and pipelines helped identify potential genes responsible for lignin deconstruction. (The JGI also conducted RNA sequencing and alignment to the …
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