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… scientist at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … or DRI for short.  A kaleidoscope of structure-function data To study DRI experimentally, Blaby-Haas, Grosjean and … sequencing and computational analysis that enable systems-based scientific approaches to these challenges.  …

Dr. Visel joined the DOE Joint Genome Institute in 2010. As the Deputy for Science … Institute in Hanover, Germany, where he developed novel tools for large-scale in situ gene expression analysis in … for elucidating the gene regulatory landscape of vertebrate genomes, which led to the discovery of thousands of genetic …

Machine learning methods were applied on sequenced fungal genomes to classify gene families. The Science As a proof of … of fungi, by lifestyles. The machine “learned” to identify data generated in part through the 1000 Fungal Genomes … fungal lifestyles of saprobes and pathogens based on the data provided. In this proof of concept test, the team …

Repeats) is the leading tool for accurately editing genomes, its effectiveness has historically been limited due to the lack of robust tools available for carrying CRISPR into microorganisms. … monitor loss- and gain-of-function. The study’s analytical data shows peaks and valleys in secondary metabolites as …

… for the design and maintenance of the Integrated Microbial Genomes (IMG) data warehouse, and integration of genomic and metagenomic data with transcriptomics and proteomics data. …

Program , along with Jenny Mortimer, Director of Plant Systems Biology at the Joint BioEnergy Institute (JBEI). … it makes its sequencing, synthesis, metabolomics and data analyses capabilities available on a peer-reviewed … (uM etc).  … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility …

… in fungi. The Science Changing an A, C, T or G in a genome sequence can lead to changes in protein structures … 5mC is an important piece of how they regulate their genomes, but is not well understood in fungi. A team of … genome-wide regulation and cataloging them in JGI’s fungal portal MycoCosm. … The work conducted by the US Department …

Dr. Frederik Schulz joined the DOE Joint Genome Institute in 2016 and is leading the New Lineages of … eukaryotic microbes and viruses in environmental sequence data. Dr. Schulz employs multi-omics (metagenomics, … ecological roles of microeukaryotes in terrestrial ecosystems. Additionally, Dr. Schulz is leading a DTRA-funded …

… included researchers at the U.S. Department of Energy Joint Genome Institute (JGI), a DOE Office of Science User … a team of researchers sought to disrupt every gene in the genome with CRISPR-Cas9 in order to interrogate each one’s … a pool of sgRNA sequences: six for every gene in the genome. The JGI  DNA Synthesis Science team synthesized …

Northen’s research is focused on using metabolomics to link genomes with environments to understand how webs of microbes … mass spectrometry approaches and model laboratory ecosystems (EcoFABs). … Trent Northen is the Metabolomics … Populus across genotypes and environments. 2024 Nature Sci Data. 11, 339. https://doi.org/10.1038/s41597-024-03069-7  …