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A Redesign for Yeast’s Genome, Chromosome by Chromosome
… To engineer yeast to do more, and understand genomes in general, Jef Boeke, Weimin Zhang … and Leslie Mitchell (Neochromosome) have worked to replace yeast’s native chromosomes with synthetic versions. This …
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Fungus Fuels Tree Growth
… poplar, a potential biofuel feedstock.     The Science The fungus  Mortierella elongata enjoys a dual lifestyle; it can … in order to get  M. elongata and  I. europaea  genomes sequenced and annotated for this study. The team found that, unlike pathogenic or mycorrhizal fungi (mutualist symbionts …
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Microbial Program
… The JGI’s Microbial Program focuses on using cutting-edge sequencing, annotation and analysis techniques to explore the vast and … The Microbial Program focuses on using advanced sequencing technologies to … resequencing, RNA sequencing and epigenomics. Expansion of sequence space:  The JGI generates reference genomes from …
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A Cost-Efficient Way to Convert Yeast into a Cell Factory for Hydroxyapatite
… Innovative technology from this biomanufacturing collaboration is … products from human waste. They   genetically modified yeast to efficiently convert elements present in urine to … Berkeley Lab, JGI and Foundry researchers realized that the yeast   Saccharomyces boulardii  was naturally performing …
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Mapping Heat Resistance in Yeasts
… A new approach for improving functional annotation in fungal … genes that promote heat resistance in the brewer’s/baker’s yeast Saccharomyces cerevisiae , allowing this species to … then used a series of random insertions of a foreign DNA sequence to generate a huge pool of mutants, each containing …
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The fungus that made itself at home
… from similar organisms, researchers have gained insights on why the dry rot ( Serpula lacrymans ) is so destructive in … adapting to thrive in built environments. Summary Unlike white rots, brown rots break down only the cellulose … Serpula species, S. himantioides from Europe, that was sequenced and analyzed by the JGI. The researchers found …
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Data Policy
… Data produced and released by the US Department of Energy (DOE) Joint Genome … Embargo : A period in which data is not publicly available in JGI systems or outside … For sequencing or metabolomics projects: data are subject to a  one-year embargo .  For each data or …
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Genome, transcriptome and secretome analyses of the antagonistic, yeast-like fungus Aureobasidium pullulans to identify potential biocontrol genes
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Making a Lichen Together
… first time, a team analyzes the transcriptomes of a lichen fungus and alga to understand their partnership more … fungus’ tissue. If you’re a Marvel Comics fan, you might liken the symbiotic relationship to that of Eddie Brock and … nitrocellulose filters in Petri dishes. The scientists also sequenced the fungus and photobiont’s genomes and compared …
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An Addiction Crucial to a Fungus’ Reproduction
… A fungus relies on bacteria to regulate key components of its … endobacteria establishing control over reproduction was a likely key to this evolutionary transition. Using this … with the fungi and bacteria, while the DOE JGI team sequenced and annotated a host genome (Rm ATCC 52813) as …
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Analyze Data
… The JGI supports the entire data life cycle — from experimental design to reuse. Armed with the high-quality data we generate, tools like artificial intelligence can empower the global research … Chief Informatics Officer …
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Mining New Frontiers: The Critical Minerals and Materials Joint Call
… The Joint Genome Institute and the Molecular Foundry have launched a joint Critical Minerals and Materials … Access to the Molecular Foundry and use of JGI capabilities … For DNA synthesis projects, JGI ships physical materials like expression constructs or sgRNA libraries to the user. …
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