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… about the basics of genome mining, which is using DNA sequence to identify and interpret biosynthetic, secondary … biological perspective, like what was this bacterium, and why did your group want to study it? Marnix Medema: You mean … had to scale also by orders of magnitude. And that’s why Satria figured out some new clever tricks to make an …

… tool BOOST , which provides a suite of tools to automate sequence design for assembly by Gibson, Yeast recombination …

… (see Auspice Statement below) for the generation of sequence or metabolomic data, DNA synthesized, and any other …

… at genomes and seeing where the really hard things to sequence were, and wondering what those … what those were … functional was these secondary metabolite pathways. So why was that? What is it about secondary metabolite pathways … favorite examples of a secondary metabolite producer, and why they produce those metabolites? MARC: Well, I’m really …

… the foundation for a large-scale CSP proposal submission. Sequence requests should not exceed 3 Tb in total. Proposals …

… The genes are pretty much 100% identical. We don't know why one is expressed over the other. As far as whether we're … usually serve as dimers, and then they will bind to certain sequences of DNA. And when they bind to those certain … are capable of making those strange ring systems. JACKIE: Why? Is it just because of ring strain or is it-- I guess, …

… able to explore DNA sequencing and actually get to the DNA sequence – sequences for the genes that code for the … Something that’s you know …  ALISON: Central! DAN: That’s why they called it that! But for, maybe, people who are less … biology perspective, like if you have a cluster of genes, why can’t you just engineer you know, a promoter or an …

… The deliverables can range from raw sequence data to well-annotated assembled genomes to … listing of approved proposals can be found here. All sequence data will be accessible on the JGI Data Portal. … How much will it cost me to sequence or synthesize my target or obtain metabolomics data? …

… learned a lot so much history from this conversation about why the ocean was basically unexplored until the 70s, and … about his move to microbiology, about drug discovery and why it’s so hard to succeed, and we talk about an ongoing … forward to seeing the data when it finally gets off the sequencers. The pandemic has obviously slowed JGI down a …

… of living. The Impact Microbes help regulate the global carbon cycle — fixing, transforming, and respiring carbon. … of SAR324 cells and their gene expression, the team then sequenced community genomes and expressed gene transcripts … ecotypes because, historically, they have used the sequence of a “marker gene,” namely the 16S ribosomal RNA …