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… to conduct genome-wide screens and explore biosynthetic pathway. Thus far, the JGI has deployed CRAGE to … domesticate some 60 strains, inserting into them a genetic sequence that acts as a “landing pad.” Mouncey adds, … “Once you have a landing pad in a strain, you can deliver multiple types of payloads, such as individual genes, whole …

… cutting-edge capabilities to help advance their science by generating data in three overarching categories: DNA … , Biodesign and Metabolomics .  Many users rely on a multifaceted combination of genomic, transcriptomic, … time, the team is expanding current capabilities in strain engineering and functional assays and supporting new …

… that uses a carbon fixation process known as the C4 pathway, which particularly helps plants thrive in warm, … at Lawrence Berkeley National Laboratory (Berkeley Lab), generated genome sequences for nearly 600 green millet … that green millet was introduced into the United States multiple times from Eurasia. The team also identified a gene …

… technology to help access complicated natural product gene clusters, and we’re all really excited about that, and … of the natural product. So that was my PhD study, and then towards the end of my PhD study, then recombinant DNA … CRISPR technology, anything as genome editing, genome engineering, to make something even better and making more …

… enabled by the JGI DNA Synthesis Science Program. Fashioning DNA outside a cell is key to interrogating what genes do, how they work, and applying them to environmental … our group. It’s enabled us to accelerate gene, enzymes, and pathway discovery approaches and provided the resources …

… led a team that  recently published work on the JGI Plant Gene Atlas in  Nucleic Acids Research . The project spans 15 … time course data from two ecotypes of  Panicum hallii and multiple switchgrass ( Panicum virgatum ) experimental data. … urea showed nitrogen and amino acid-specific metabolic pathways were overrepresented in the nitrate-subjected …

… Multi-species assays yield an unprecedented view of plant evolution and adaptation.    Understanding how genes are regulated is like deciphering the complex wiring … gene expression maps, providing insight into how regulatory pathways control specific cell types. “A lot of these …

… Facility, the JGI serves more than 2,500 users that predominately come from the public sector: academic and government … including User Facilities like the JGI, through its Genesis Mission. Launched in 2025, the initiative aims to … and AI agents to solve key national challenges. The Genesis Mission consortium will connect leading industry and …

… Understanding the shared genetic toolkit of ancestral and present-day … related genes in more complex plants that could be applied toward DOE-relevant bioenergy and environmental interests.  … ) conducted by the US Department of Energy Joint Genome Institute ( https://ror.org/04xm1d337 ), a DOE …

… Research uncovers the genetic foundations that helped plants conquer land over 600 million years ago. The Science By studying the genes of land plants’ closest algal relative,  … to land. Key gene groups involved in stress tolerance and multicellularity enabled plants to develop complex …

… Fine-tuning metabolic gene expression helps identify variants in yeast genes. The … library approach to tuning gene expression in metabolic pathways. Compared to the traditional way, which leverages … to the results of the sugar-related tests, they pinpointed multiple genes that were previously missed in knock-out …