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… to conduct genome-wide screens and explore biosynthetic pathway. Thus far, the JGI has deployed CRAGE to … domesticate some 60 strains, inserting into them a genetic sequence that acts as a “landing pad.” Mouncey adds, … “Once you have a landing pad in a strain, you can deliver multiple types of payloads, such as individual genes, whole …

… that uses a carbon fixation process known as the C4 pathway, which particularly helps plants thrive in warm, … at Lawrence Berkeley National Laboratory (Berkeley Lab), generated genome sequences for nearly 600 green millet … that green millet was introduced into the United States multiple times from Eurasia. The team also identified a gene …

… technology to help access complicated natural product gene clusters, and we’re all really excited about that, and … of the natural product. So that was my PhD study, and then towards the end of my PhD study, then recombinant DNA … CRISPR technology, anything as genome editing, genome engineering, to make something even better and making more …

… is focused on genomic science projects that address sustainable biofuel and bioproducts production, leveraging … approaches to unravel functional capabilities of plants, microbes and microbial communities, global carbon … and track record of the applicant.  Learn about the general review process or get details on the internal …

… led a team that  recently published work on the JGI Plant Gene Atlas in  Nucleic Acids Research . The project spans 15 … time course data from two ecotypes of  Panicum hallii and multiple switchgrass ( Panicum virgatum ) experimental data. … urea showed nitrogen and amino acid-specific metabolic pathways were overrepresented in the nitrate-subjected …

… enabled by the JGI DNA Synthesis Science Program. Fashioning DNA outside a cell is key to interrogating what genes do, how they work, and applying them to environmental … our group. It’s enabled us to accelerate gene, enzymes, and pathway discovery approaches and provided the resources …

Understanding the shared genetic toolkit of ancestral and present-day … related genes in more complex plants that could be applied toward DOE-relevant bioenergy and environmental interests.  …

Fine-tuning metabolic gene expression helps identify variants in yeast genes. The … library approach to tuning gene expression in metabolic pathways. Compared to the traditional way, which leverages … to the results of the sugar-related tests, they pinpointed multiple genes that were previously missed in knock-out …

See below for examples of successful Letters of Intent to our Community Science Program Large-Scale Call, as … PIs who drafted them.  … Elucidating Sphagnum microbiome genetic interactions for improved growth at elevated … strategies in a cosmopolitan and abundant soil bacterium: genetic microdiversity or core metabolic flexibility? … …

Research uncovers the genetic foundations that helped plants conquer land over 600 … to land. Key gene groups involved in stress tolerance and multicellularity enabled plants to develop complex … no. DE-AC02-05CH11231. P.-M.D is supported by the project Engineering Nitrogen Symbiosis for Africa (ENSA) currently …

… to customize the crop for additional end products. The genetic diversity within this set of plants, each with a … with switchgrass biology, information that could be useful toward the DOE’s interest in harnessing the crop as a … of clonally propagated plants to address these questions.” Multiple collection methods were applied to gather the …