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… team in collaboration with the JGI. Conserved Fungal Genes of Unknown Function offer a collection of fungal genes conserved across the fungal tree of life or its major …

… they could be a whole bunch of things. When we started testing our molecules, we found the targets to be diverse … then of course using modern phylogenetic tools measuring genes, the 16S gene, and comparing it with everything that’s … we found out what it was pretty soon. We started testing it in collaboration with the National Cancer …

… metabolic gene expression helps identify variants in yeast genes. The Science Scientists have developed a more nuanced … allowed researchers to identify variations of essential genes in metabolic networks that were missed using … screens. These results show that this singular library synthesized by JGI was versatile enough for use in multiple …

Do you think that they always cluster or could the genes be separated on a genome?  Dan: Oh yeah. It’s biology … how that molecule is built and you should be able to find genes in the organism in its sequence that encode for that … discovery.  DAN: Tell me about that biological activity testing then because I know that I have been out of that …

RNA alongside. That really helps us to determine where genes start and end and really help improve our annotation. … just give them the data output, but we tell them which genes may be affected by that and how. So a lot of goes into … equivalent is for more complex organisms, or hundreds of kb synthesized, and so on The project must fit within the DOE’s …

… raw sequence data to well-annotated assembled genomes to synthesized DNA constructs to metabolomics data, depending …

… and communication. Studying how these compounds are biosynthesized and their roles in the environment, can unlock …

… into functional assessments. This is done by synthesizing genes, pathways, and whole chromosomes for bioenergy, …

Z. & Rubin E.M. Metagenomic discovery of biomass-degrading genes and genomes from cow rumen. Science 331, 463-7 (2011). …