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… is like, what’s your origin story in natural products? Why are you doing this? JACLYN WINTER: I’ll kind of go back … that I never anticipated starting– that’s not why I came to the University of Utah– is looking at the … to grow. If you hear Nigel talk, he is very interested in sequencing a lot more natural product-heavy culture …

… learned a lot so much history from this conversation about why the ocean was basically unexplored until the 70s, and … about his move to microbiology, about drug discovery and why it’s so hard to succeed, and we talk about an ongoing … bring it into the lab. And I think that criterion explains why the natural products in the ocean weren’t studied up …

… other omics technologies.  The exponential growth of DNA sequencing data, coupled with recent computational … (Nature 2019). Other projects in the group include the sequencing and comparative analysis of thousands of archaeal … et al. (2014) Genomic Encyclopedia of Bacteria and Archaea: Sequencing a Myriad of Type Strains. PLoS Biology …

… The genes are pretty much 100% identical. We don't know why one is expressed over the other. As far as whether we're … technology.] BETSY PARKINSON: OK. DNA affinity purification sequencing. And so the way this essentially works is you … at the college level. So-- DAN: Yeah, for sure. And JGI is sequencing quite a few of the things that end up-- BETSY …

… NIGEL MOUNCEY: Oh, sure. I think our legacy obviously is in sequencing.  DAN: Of course.  NIGEL MOUNCEY: Sequencing the wazoo out of anything that’s relevant to the … so it’s really functional genomics. And there’s a lot of sequencing based approaches, of course, now that we can use …

… your interest in getting into natural products. DAN: Why are you here at SIMB? AARON PURI: Yeah. Thanks Jackie. … JGI and this was before they were integrated. So I thought, why not feed it in there. And I went to group meeting and … AARON PURI: Yeah. No, you’re exactly right. So you can see why these are tightly regulated. DAN: For sure. For sure. …

… For accepted proposals, sequencing, synthesis, metabolomics and analysis will be … No, the proposal is only for sequencing, metabolomics and/or synthesis effort at the JGI. … While, in general, requests will be for sequencing and its analysis, investigators are encouraged to …

… of critical minerals and materials. For accepted proposals, sequencing, synthesis, metabolomics and analysis will be …

… to DOE mission is appropriate. For accepted proposals, sequencing, synthesis, metabolomics and analysis will be …

… things, because a lot of what we do at JGI in terms of the sequencing that we do is very people-disconnected, and … methicillin-resistant Staphylococcus aureus . Can you share why finding treatments for these microbes is so important? … to understand more about plant natural products? We have sequencing facilities, DNA synthesis, metabolomics. Where do …

… A Letter of Intent is required. For accepted proposals, sequencing, synthesis, metabolomics and analysis will be …

… manager may then schedule and allocate resources for DNA sequencing. … Guidance on international shipments can be found in the Sequencing Sample Overview file in our HERE (TK) .  Note: … appropriate alternatives. See specific protocols within the Sequencing Sample Overview file in our Documents Center, and …