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… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … How can you design a drug, right? You design drugs  based on certain knowledge, without which, you know… If you … natural product versions of enediyne molecules, there’s a whole bunch of other atoms that can either stabilize the …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the … identifying genes to that toxin, but it’s opened up this whole area of environmental health that we’re now working … to really challenge me, and as being sort of a laboratory based scientist, to get out onto the ocean and do ocean …

… well-integrated across JGI departments to ensure a robust offering of sequencing capabilities and products to our users. This includes scaling the technologies and enabling state-of-the-art sample processing and sequencing capabilities. … profiling transcription factor binding sites across entire genomes. This technology has been further scaled to a …

… Genomics call is to enable users to perform state-of-the-art functional genomics research and to help them … ‘omics capabilities to enhance understanding of gene and genome function, particularly those not readily achievable … may be submitted to the JGI at any time using a simple web-based form and are reviewed annually. For accepted …

… got Kate here today, and we wanted to talk to her about a whole list of things. So we have a Scripps background shared … was really before– or kind of around about when the first genome sequencing was done. But natural products– marine … is a whole bunch of information that maybe never makes its publication. And these are little tips, you know, how to …

… The Genome Insider podcast brings listeners into the science … — JGI Users — and dives into their work on all kinds of organisms, from plants and fungi to microbes and viruses. …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … and interesting biosynthetic pathway, and I’ll have to do a whole show on it one of these days. If you listen to the … you’d like to read more about this, I highly recommend his publication last year, “The Biosynthetic Diversity of the …

… for researchers to request the capabilities and expertise of multiple DOE National User Facilities in one research … Successful applications will focus on high-risk/high-payoff proposals within the focused topic areas that can be … provides customized analysis, the JGI also participates in publication of results. …

… this identification, metabolomics enables functional genome annotation, improves understanding of the role small molecules play in diverse biological … advanced liquid chromatography mass spectrometry (LC-MS) based methods in combination with advanced computational …

… to more easily integrate the expertise and capabilities of multiple Department of Energy Office of Science National User Facilities into … provides customized analysis, the JGI also participates in publication of results. … as needed), and the work plan is written into a Statement of Work document. …

… month, just like I promised. Now I just have to make this whole “on-time thing” a habit! I’m really not good at that, … exposure to working with Streptomyces, learning more about genome mining, as well as isolation and a little bit of … JACKIE: So they're very much developed their own language based on-- DAN: Sure. JACKIE: Yeah, they've evolved. That's …

… Our lab is using mass spectrometry based metabolite profiling to provide direct biochemical datasets to improve our understanding of microbial metabolism. Of particular interest is …