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… … Dan Udwary: You’re listening to the Department of Energy Joint Genome Institute’s Natural … center and a lot of the really important recent events in data analysis and secondary metabolism over the last decade … we, for example, are really interested in metagenomes and microbiomes and figuring out which gene clusters are …

… successful letters of intent and submissions at the bottom of the page.  … Review the list of open calls ; click on … begin, and all CSP proposals are subject to JGI policies on Data Release and Publication .   Except for applicants to the CSP New …

… is a fungal natural product which is a liver toxin when humans accidentally eat it, but it has a really fun and … rich and underappreciated. And we’ve worked both with the microbiome. So, with symbiotic bacteria that live in animals … you’d like to read more about this, I highly recommend his publication last year, “The Biosynthetic Diversity of the …

Below is a brief description of the process needed to prepare and ship samples for sequencing by the JGI. … GenTegra RNA Preparation Procedure … 1) Complete Sample Metadata form Sample metadata is collected via spreadsheet or … Project Manager (PM) a list of organism names (or for metagenomes, sample names).  Need help naming your organisms? …

… him about more recent work like ActDES, which is a curated database of actinobacteria for evolutionary studies, and … talk about secondary metabolism because they are useful for humankind. We forget that the real champions of the story … of natural product biosynthesis in bacteria ” The ActDES publication came out after we talked. It looks like a great …

MARC: Well, I’m really biased and I like the bugs in the microbiome. So a lot of my work is as focused on insects As … we’re also excited about antibiotics that might not be for human use. So things that we might be able to use against … for a company. Personally, that was my first taste of big data if you want, maybe it’s medium data now. But at the …

The mission of the Joint Genome Institute is to serve the scientific community as a user facility … of Science through high performance computing (HPC) and data analysis.  The DOE Systems Biology Knowledgebase ( … more customized analysis, the JGI also participates in publication of results. … Submission … More on Sequencing …

… episode 9 of Natural Prodcast. This week, Alison and I talk to Roger Linington, from Simon Fraser University in British … or NPAtlas, a freely accessible natural products structure database, which is going to be just invaluable to the … And are any of those bits of chemical space relevant to human health? You can imagine that compounds found in nature …

… for fundamental growth, provide critical advantages to the organisms producing them, and are often involved in … cell- and cell free-based expression platforms, tools and data for deciphering regulatory networks, and refining … of transcription factors and determine their binding sites across multiple genomes. Computational prediction of …

… is throughout nature, except maybe for animals and humans, not as much. You know, we have this human centric … the sponges or other things. And we know lots more about microbiomes and symbionts that live with other organisms, … has been really crucial.  DAN: Yeah, yeah. The more data you generate, the more knowledge you can generate. So …

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