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Mining Metagenomes for Cas Proteins
… Institute.  The Science Researchers report the discovery of miniature Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) associated proteins that can target single-stranded … by searching for Cas12d homologs across IMG/M’s assembled metagenomic data. It turned out that some of these were …
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Plant Program
… to current problems facing humanity. A major focus are biofuel feedstock species and plant-microbe interactions, … a plant based bioeconomy where plants are a major source of chemical production and contribute to a healthier planet … The Plant Program advances our understanding of plants’ biological and ecological roles to foster …
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Natural Prodcast Episode 14: Nigel Mouncey
… DAN: Hello, everyone, and Welcome back for Episode 14 of Natural Prodcast . There’s been a lot going on, so I took … in these different organisms. We’ve now just built out a CRISPR based system that we can use to activate the … help the Society grow. And so I’ve been the chair of the publications committee for the last, what is it now, five …
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Micro-Scale Applications Group
… Micro-Scale Applications group explores the genetic makeup of natural microbial communities using a variety of cutting-edge approaches.  Our group also seeks out new approaches that utilize microfluidics/microdroplet technology in order to enhance the … offers the first quantitative Stable Isotope Probing (SIP) Metagenomics pipeline that utilizes internal analytical …
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Natural Prodcast Episode 2: The Primer, Part 2
… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the science and scientists of secondary metabolism.  DAN: Hi, again. This is Dan, and … through the stories I told you about geosmin, which is a bacterial sacred metabolite, and ergot alkaloids come from …
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Biodesign
… automations for DNA design, assembly and analysis Overview of biodesign products The JGI Biodesign platform enables … Check out our organism-agnostic CRISPR gRNA design tool  … BOOST provides a suite of tools to automate sequence design for assembly by Gibson, … Software Engineers in the Synthetic Biology Informatics Group …
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Natural Prodcast Episode 21: Elizabeth Parkinson
… schedule. This should be coming out on the first Thursday of the month, just like I promised. Now I just have to make … Parkinson from Purdue University. She’s in the Department of Chemistry and the Department of Medicinal Chemistry and … about several different pieces of her work, including bacterial quorum sensing and its effects on regulation of …
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Natural Prodcast Episode 5: Brad Moore
… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … Patrick would spend time between our two laboratories doing metagenomics, some genomics. We were a little concerned … in a microalgae. There were four genes there. Not like a bacterial gene cluster, but they were still clustered in the …
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JGI@25
… Celebrating 25 years of genomics research 2022 marked the JGI’s 25th anniversary. We revisited a number of notable achievements that showcase our collaborations and … the JGI’s 25th anniversary, the JGI mural references dozens of iconic JGI contributions to advancing the frontiers of …
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Frequently Asked Questions: Project Management
… You can visit the Products & Offerings section of our website for more details, including a downloadable pdf of products categorized by Science Program.  … The majority of JGI projects come from the user community. Find out about … proposal calls and proposal submission, as well as examples of approved proposals, please visit the Proposals FAQ .  …
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Rex Malmstrom
… Dr. Malmstrom is a Staff Scientist and leader of the Microscale Applications group. Before joining the JGI … and carbon consumption of SAR11 bacteria, the most abundant bacterial group in the ocean. Later during his postdoctoral … His group also handles the Stable Isotope Probing (SIP) Metagenomics pipeline  that reveals in situ functional …
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Natural Prodcast Episode 19: Bill Fenical
… for you here today. We got the opportunity to talk to one of the real legends of natural products, Professor Bill Fenical from Scripps Institution of … In this episode, Natural Prodcast talks to the legendary Prof William Fenical of Scripps Institution of Oceanography in …
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