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… sparked your interest, and you want to learn more, then I highly recommend David Hopwood’s book called  “Streptomyces … in a year. And that would be a good thing. That would be high. ALISON: I mean, I’ve heard some statistic about how … and the 90s. And so we started to be able to explore DNA sequencing and actually get to the DNA sequence – sequences …

… FY 2026 DOE Metrics Sequencing Quarter Total Bases (Trillions) Operating Hours …     Q4 2026 175     2,208     *Includes Illumina and PacBio sequencing platforms. **Operating Hours target is based on … lab activities related to the return-to-work plan in response to the pandemic.   FY 2019 Number of Unique Users …

… and I think that was a very good idea because it really alleviates the amount of stress around this, especially … least a certain level of similarity. So if similarity was higher than a certain kind of volume. And if you do that, … an antifungal. It could also be perhaps eliciting a response by another bacterium, for example. But at least we …

… A Letter of Intent is required. For accepted proposals, sequencing, synthesis, metabolomics and analysis will be … provides customized analysis, the JGI also participates in publication of results. …

… and expertise. These collaborations have yielded numerous, high-quality outputs, such as data, publications and software. The JGI supports the entire data … of users. Each portal lists a contact, or you can reach out via the form on our website.   …

… and track record of the applicant. For accepted proposals, sequencing, synthesis, metabolomics and analysis will be … are approved will receive further instructions via email.   Human or animal disease-related work will NOT …

… they then ship samples—such as DNA and RNA for sequencing—to JGI. Users are responsible for covering the … proposal include snRNAseq and snATACseq library prep and sequencing? …

… to hear about what folks are up to in a slightly different niche in chemical enzymology. So, we talked about her JGI … And you want to have good binding to your substrate and high turnovers. But if you have those things, can you also … off– JACKIE WINTER: No. ALISON NARAYAN: Often, they’re abbreviated too from alpha ketoglutarate to just AKGs. In my lab, …

… genomic data, open to all researchers. Book a session via the appointment calendar for technical help, feedback or … access to information regarding genome and metagenome sequencing projects, and their associated metadata, around … all JGI genomic databases and analytical tools for all JGI sequencing projects. In 2021, the JGI launched the Data …

… get, which is already a fairly small number. We’re a very niche podcast. And so maybe if we can combine two things … and do this stuff as opposed to– I think like a perfectly viable career track in natural products, and especially if … And I think a lot of times, too, when we even look at publications, it’s always positive data, right? No one ever …

… first described by Stanley and Konopa in 1985, which highlights our skewed understanding of microbial metabolism … to only three phyla. The Woyke group uses single-cell sequencing as a means to begin filling this gap. A primary … the metabolic potential of uncultivated lineages is of high value to establish models and hypotheses, experimental …

… challenge is, as the listeners know, even when you find a highly potent active compound that has a good cytotoxicity … different options before you find something that could be viable for development as an antibiotic. ALISON TAKEMURA: … I think on COVID that we’re getting ready to submit for publication and have found some interesting hits for that as …