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CSP Large Scale Call
… and track record of the applicant. For accepted proposals, sequencing, synthesis, metabolomics and analysis will be … are approved will receive further instructions via email.   Human or animal disease-related work will NOT …
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DNA Synthesis Program
… tools that enhance biofuel production and biosystem design. High-throughput design and synthesis capabilities accelerate … JGI as a tool for extracting specific sequence regions in a high throughput manner from any genome, and facilitate whole …
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Natural Prodcast Episode 3: The Primer, Part 3
… sparked your interest, and you want to learn more, then I highly recommend David Hopwood’s book called  “Streptomyces … and the 90s. And so we started to be able to explore DNA sequencing and actually get to the DNA sequence – sequences … ,  Spotify ,  Stitcher , directly with the  RSS link , and via most other commonly-used podcast feeds. Please …
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Natural Prodcast Episode 22: Alison Narayan
… to hear about what folks are up to in a slightly different niche in chemical enzymology. So, we talked about her JGI … And you want to have good binding to your substrate and high turnovers. But if you have those things, can you also … off– JACKIE WINTER: No. ALISON NARAYAN: Often, they’re abbreviated too from alpha ketoglutarate to just AKGs. In my lab, …
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Natural Prodcast Episode 24: Jackie Winter and SMC
… get, which is already a fairly small number. We’re a very niche podcast. And so maybe if we can combine two things … and do this stuff as opposed to– I think like a perfectly viable career track in natural products, and especially if … And I think a lot of times, too, when we even look at publications, it’s always positive data, right? No one ever …
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Frequently Asked Questions: Proposal Submission
… proposals are subject to JGI policies on Data Release and Publication .   Except for applicants to the CSP New … contact us in advance for advice. … For accepted proposals, sequencing, synthesis, metabolomics and analysis will be … Energy’s funding of the JGI. … No, the proposal is only for sequencing, metabolomics and/or synthesis effort at the JGI. …
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Natural Prodcast Episode 17: Cassandra Quave
… challenge is, as the listeners know, even when you find a highly potent active compound that has a good cytotoxicity … different options before you find something that could be viable for development as an antibiotic. ALISON TAKEMURA: … I think on COVID that we’re getting ready to submit for publication and have found some interesting hits for that as …
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Natural Prodcast Episode 15: Katherine Duncan
… got quite a lot of lipids in them. But from an economically viable point of view, they haven’t quite worked. And as a … more economic, they also would like to extract some high– what they term “high value–“ Dan Udwary: Right. Kate … is a whole bunch of information that maybe never makes its publication. And these are little tips, you know, how to …
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Natural Prodcast Episode 7: Ben Shen
… started collaborating with Ben and his group to work on sequencing, synthesis and genome mining technology to help … one, first that we call antibody drug conjugates, abbreviated as “ADC”, was approved in the year 2000, and utilize … where in particular areas, or particularly as by ecological niches, the natural product could be there. So this has …
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Secondary Metabolites Program
… developing cell-free based systems to express BGCs that alleviate the constraints of cells and allow for substrates to … We have developed Regulon Identification by in vitro-sequencing (RIViT-seq) to identify RNA polymerase-sigma … We are also utilizing DNA-Affinity Purification (DAP) sequencing to express hundreds of transcription factors and …
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Single Cell Research Group
… first described by Stanley and Konopa in 1985, which highlights our skewed understanding of microbial metabolism … to only three phyla. The Woyke group uses single-cell sequencing as a means to begin filling this gap. A primary … … Research Interests … Former Lab Members … Selected Publications … For further details, please reach out to the …
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Fungal & Algal Program
… environmental sustainability, and bioproducts. By sequencing and analyzing the genomes of these organisms, the … … The Fungal & Algal Program harnesses cutting-edge sequencing technologies and advanced genomic analysis to … and biogeochemistry. The program’s focus is on large-scale sequencing efforts that survey the vast phylogenetic and …
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