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The Fungal & Algal Program explores the vast diversity of fungi and algae to unlock their potential for bioenergy, … and bioproducts. By sequencing and analyzing the genomes of these organisms, the program investigates the … This research helps translate their genomic potential into practical applications, including sustainable biofuels, …

… — before any work can begin, including the submission of samples for sequencing, or the submission of sequencing data for synthesis. This agreement, required … rights in technical data, project reporting to the DOE, and publication requirements. An official with authority is …

Genomics call is to enable users to perform state-of-the-art functional genomics research and to help them translate genomic information into biological function.  The emphasis is on projects … ‘omics capabilities to enhance understanding of gene and genome function, particularly those not readily achievable …

… basic ideas of the science of natural products, and we dive into the very early history of the field. If you continue … that – I want to say like lipid bilayer, you know, in the cell.  DAN: It depends on lifestyle. So there are lots of … think of bacteria. You think of bacteria as sort of these single celled organisms, kind of all over. But these kinds …

… and bioenergy crop enhancement. The program aims to tap into the largely unexplored biochemical diversity within … (BGCs), advancing pathway analysis, optimization of cell- and cell free-based expression platforms, tools and … factors and determine their binding sites across multiple genomes. Computational prediction of heterologous …

… cohesive data standards, the JGI partners with a number of facilities.  … Through its partnership with NERSC and the … analyses, such as metabolic modeling, that go well beyond genome annotation and analysis. The JGI and KBase seek to … seamlessly access and analyze data on scales ranging from single genes and individual genomes to metagenomes to …

So maybe we could start with that background – what got you into secondary metabolism, besides being forced to work with … in putting antibiotics together, getting them out of the cell letting them do their dirty work. So that’s one arm. … to go in the next couple years. And hopefully, some of the insights that we glean from that will be broadly applicable …

… to more easily integrate the expertise and capabilities of multiple Department of Energy Office of Science National User Facilities into their research. In recognition of the increasingly … provides customized analysis, the JGI also participates in publication of results. … All proposals undergo technical …

Bill is a pioneer of marine natural products, getting into the ocean and looking for molecules from the very … we want a chemist to study the ocean. And I didn’t find a single job advertisement. But one day, I decided to really … that the molecules out there would be toxic to cancer cells. And that started something big. Because at that time, …

… always wanted to write a book but it’s really hard to break into that area. I mean you have to secure an agent and … I think on COVID that we’re getting ready to submit for publication and have found some interesting hits for that as … and other natural product libraries, so not relying on single crystal X-ray diffraction, but looking actually at …

The JGI Project Management Office carries out a number of activities to facilitate … of your sequencing project at any time by logging on to the Genome Portals using your JGI login. After … access your data, share with collaborators, and coordinate publication with JGI scientists. Synthetic DNA constructs …