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… … DAN: You’re listening to the US. .Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … than screening in the past, is in the types of pathogens or challenges where we’re putting these bugs and assays … hundred examples, they were able to put dates on when major changes in the genes and chemistry happen, which I …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … it’s really moved us into directions that, really, I think, challenges us as a laboratory. Initially, my group really … an impact, like the domoic acid story, and be able to have global science-type connections, and be able to use our …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … for fungi. And we talk a lot about some of the technical challenges to that, most of which seem to be history.   I … to grad school in microbiology. And certainly, I mean, the majority of it was focused on bacteria. And this was at MIT. …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … the idea of working on harder organisms, with the kinds of challenges that usually lead to surprises and really great … you’d like to read more about this, I highly recommend his publication last year, “The Biosynthetic Diversity of the …

… … DAN UDWARY: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast– a … Dorrestein – the molecular networking, you can have a global view on the chemical diversity of metabolism. We … of natural product biosynthesis in bacteria ” The ActDES publication came out after we talked. It looks like a great …

Welcome back to Natural Prodcast. This continues the series of interviews we recorded at the Society for Industrial … all of these molecules. We know very little about what the majority of them do. We have in-depth biological studies on … work with in the lab. That’s something– ancestral protein prediction, reconstruction is a whole field. There’s a lot …

… on genomic science projects that address sustainable biofuel and bioproducts production, leveraging systems-based … capabilities of plants, microbes and microbial communities, global carbon and nutrient cycling, and biogeochemistry — … All proposals will be externally peer-reviewed for scientific merit, DOE mission relevance, proposed data …

I didn’t really know what that meant.  I was a chemistry major after being an optical engineering major after which … And we’ve done some work with those and have a couple of publications out there on the chemistry. There’s so much … giving access to various different groups and overcoming challenges that we have along the way based on our …

… … Dan Udwary: You’re listening to the Department of Energy Joint Genome Institute’s Natural Prodcast, a … even know of your existence back then. So there was no hostilities. Dan Udwary: That is certain, yes. So welcome. I … grad student with Michael. And we did it together. Did the global analysis of biosynthetic gene clusters across, well, …

I can say.  DAN: Sure, sure.  NIGEL MOUNCEY: So we had two major natural products projects that we had in my group … about secondary metabolites. And we thought about grand challenges that exist in the secondary metabolites … help the Society grow. And so I’ve been the chair of the publications committee for the last, what is it now, five …

JGI-led team significantly expands the global diversity of large and giant viruses. While the … population, the number of viruses in the same drop—the vast majority not harmful to humans could be even larger. Viruses … that enable systems-based scientific approaches to these challenges.  DOE’s Office of Science is the largest …

… … DAN: Welcome back for episode 9 of Natural Prodcast. This week, Alison and I talk to Roger … discovery, predominantly in diseases of importance to each host country. It was built very much on the foundations of … do a lot of mass spectrometry, everybody will bemoan the challenges associated with data analysis, and particularly, …