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It was actually when I was traveling at the end of first year University. Quite a lot of people in Europe do this … an undergraduate in chemistry. Now when I was in fourth year, we had a choice to do an integrated master’s program … like. I was imagining some massive contraption for amplifying genes. I wasn’t really sure what actinobacteria were. …

… white papers. Applicants may submit up to two proposals per year (but may be listed as co-PI on an unlimited number of …

And so a path opened itself to me, just before my senior year of college, a chance to go to the Amazon and work with … staph in general kills more people than HIV/AIDS does every year in the US and it has since 2005 even though we … they were starting to show the ability to really identify, and get crystal structures out of these mixed powders, …

… been in – working in secondary metabolism for almost 20 years now. Which when I did the math, that was a surprise to … professor at the University of Rhode Island for a couple of years before I left that to join a biotech startup. And … data that the JGI produces to try to find and identify natural product biosynthetic gene clusters and to do …

… of genome mining, which is using DNA sequence to identify and interpret biosynthetic, secondary metabolism … that, I wanted to tell a quick story. Looking back, the year was probably 2010, 2011, I was a, uh- actually, I’ve … time. So they had actually sequenced the genome a number of years earlier as one of the first Streptomyces genomes that …

… the content produced by microbes the result of millions of years of evolution. And if we could actually link terms to … evolution is acting very strongly. There is very strong purifying selection, and what matters is a final product. So it … conditions, unless it happens on the long term, millions of years. So interesting case. It could well be that some of …

… and resources.     Director's Perspective Over the last year, the U.S. Department of Energy Joint Genome Institute … who made use of our data. We completed 39,870 projects in FY24 We generated 871 Terabases of sequence We synthesized … with large-scale advanced genomic capabilities. This year we brought online the latest short-read technology, the …

… in the Peace Corps – I was there for about three and a half years – I worked at a high school. And one of the things … today who said “Oh, the ITS which we thought would identify to species”… he’s now found that some fungi have … review of Natural Prodcast on Apple Podcasts, Google, Spotify, or wherever you got the podcast. If you have a question, …

… houses Vibrio fischeri, it’s one strain and there have been years and years and years about 35-ish years, I think, now, studying … if they’re not clustered then maybe we’re not really identifying them very well. For sure. But plants certainly make …