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Evolutionary constraint facilitates interpretation of genetic variation in resequenced human genomes
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DOE Metrics
… (Trillions) Operating Hours Goal Actual Total* Actual % of Goal Goal (hours)** Actual Total Actual % Goal FY 2025 … platforms. **Operating Hours target is based on 98% of the total available hours.   FY 2024 DOE Metrics There … (Trillions) Operating Hours Goal Actual Total* Actual % of Goal Goal (hours)** Actual Total Actual % Goal FY 2024 …
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JGI@25: Tracking & Subduing the Plague of California’s Oak Woodlands
… previously unseen — is, in fact, a microscopic water mold, genetically related to such aquatic species as diatoms and … multi-institutional, multi-investigator effort was to decode the complex Phytophthora ramorum genome. The JGI … Tyler BM et al. Phytophthora genome sequences uncover evolutionary origins and mechanisms of pathogenesis . …
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Natural Prodcast Episode 1: The Primer, Part 1
… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the science and scientists of secondary metabolism.  DAN: Hey there, and welcome to the … near this tree and so there was probably some historical evolutionary event where the DNA transferred from the fungus …
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Insights into the phylogeny and coding potential of microbial dark matter
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Natural Prodcast Episode 8: Eric Schmidt
… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … end up with a different peptide, which might lead you to changes in bioactivity, and new uses for these peptides in … as the overall theme of your research aims? ERIC:  My theme changes, but currently, my research theme really focuses on …
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Genomics and Transcriptomics Analyses of the Oil-Accumulating Basidiomycete Yeast Trichosporon oleaginosus: Insights into Substrate Utilization and Alternative Evolutionary Trajectories of Fungal Mating Systems
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Metabolic and evolutionary responses of Clostridium thermocellum to genetic interventions aimed at improving ethanol production
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From Stress to Growth: The adaptive mechanisms of algae in changing Arctic waters
… ability to adapt to stress and rapid environmental changes. Researchers were able to identify specific genes … ice in the Arctic has decreased by more than 30% in terms of quantity and thickness. Replacing older, thicker ice with … production and natural fertilizers. By understanding the genetic and metabolic pathways involved in stress responses, …
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Natural Prodcast Episode 14: Nigel Mouncey
… … DAN: Hello, everyone, and Welcome back for Episode 14 of Natural Prodcast . There’s been a lot going on, so I took … my undergraduate in microbiology and then PhD in microbial genetics in the UK. And came across to the US for a couple … and we got a screening platform set up. And we got the genetic engineering set up. And we were kind of off to the …
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ORT: A workflow linking genome-scale metabolic models with reactive transport codes.
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Mitovirus and Mitochondrial Coding Sequences from Basal Fungus Entomophthora muscae
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