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Natural Prodcast Episode 12: Nadine Ziemert
… of it. So it wasn’t only chemistry or only biochemistry or genetics. It was also ecology. It was also evolution. It was … I could see a certain time span within these biosynthetic gene clusters. There’s gene fusion going on, and then I … like Streptomyces , as well. They have this typical mycelium. But they only grow in saltwater. So we’re thinking …
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Getting to the Bottom of Fungal Functions Across Earth’s Forests
… four forests, researchers have leveraged data from the 1000 Fungal Genomes project to form new connections between fungal guilds, genes and function. If a tree falls in the forest — whether … said, the 1000 Fungal Genomes project, together with other CSP projects, had sequenced over 2,000 fungal genomes. The …
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Computationally Classifying Fungal Lifestyles
… Machine learning methods were applied on sequenced fungal genomes to classify gene families. The Science As a proof of concept, … enabled in part through  JGI’s  Community Science Program (CSP) , as several approved proposals have contributed toward … Dothideomycetes genomes were conducted as part of the 1000 Fungal Genomes Project supported by the JGI Community …
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Natural Prodcast Episode 7: Ben Shen
… technology to help access complicated natural product gene clusters, and we’re all really excited about that, and … natural products of microbial origin is around 30,000 from fungal, and a 40,000 from bacteria. Okay? And among the … 100,000 bacterial strains, and a hundred thousand fungal strains. And if you believe the prediction that each …
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Hualan Liu
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Characterizing Communities: JGI Announces Latest CSP Portfolio
… calls. Nearly 200 Terabases of data are expected to be generated for the accepted proposals, said Susannah Tringe, JGI User Programs Deputy. “These new CSP projects accelerate our efforts to characterize … focus area was inter-organismal interactions, and two fungal proposals focus on symbiotic relationships. Jessie …
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Strain Engineering
… The focus of this group, in recent years, has been to bring generalizable technologies to bacteria, yeasts and algae previously with little to no genetic tools enabling heterologous expression and functional exploration.  The developed …
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Natural Prodcast Episode 3: The Primer, Part 3
… and actually get to the DNA sequence – sequences for the genes that code for the proteins that produce secondary … developed to the point that you could understand the genetics of secondary metabolism, it became possible to do … if we can improve technology, for assembly and cloning and expression, we should be able to actually make the chemical …
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Fungal Friends or Foes in Plant Roots
… other plant-associated fungi. Their analysis identified fungal gene families that help determine if these fungi act as … work was partly enabled by a JGI Community Science Program (CSP) proposal led by INRAE’s Francis Martin that contributed … Contract No. DE-AC02-05CH11231 within the framework of CSP 1974 “1KFG: Deep-sequencing of ecologically relevant …
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CreA-mediated repression of gene expression occurs at low monosaccharide levels during fungal plant biomass conversion in a time and substrate dependent manner
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Project Management Office
… DNA Synthesis and Single-Cell Genomics Vivian Ng Fungal Genomics …
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Natural Prodcast Episode 16: Marcy Balunas
… what we know is they’re quite selective in some way for antifungal activity. They are also, some of them, are … that we know there are compounds in there that are antifungal and antibacterial. But maybe there are compounds in … products is that we don’t know what all the biosynthetic gene clusters look like.  DAN: For sure.  MARCY: We have so …
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