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… capabilities support researchers exploring how to convert sequence into functional assessments. This is done by synthesizing genes, pathways, and whole chromosomes for bioenergy, … JGI Biodesign platform enables users to validate hypotheses generated from mining genomic data by designing and …

… of certain types of data to support their use by those generating data. The JGI Data Policy applies to research … not involved with the proposal under which the data were generated (e.g. not PIs or co-PIs) who wish to include … embargo starting at construct or strain delivery.  Detailed sequence information and constructs are made publicly …

… critical requirements for amplifying the JGI’s impact. Data generated from a single investment will be reused for … of microbial communities based on their metagenome sequence, in the context of reference isolate genomes … rich data such as inferred host taxonomy, conjugation potential, antibiotic resistance genes, and ecosystem …

… I was imagining some massive contraption for amplifying genes. I wasn’t really sure what actinobacteria were. Dan … of almost finished characterizing them. We’ve got genome sequences, which are just incredible. We’ve looked at the … see everything, right? You can see the full biosynthetic potential of what you’ve got. Dan Udwary: You might not know …

… I think for Natural Prodcast, I think the question that generally comes up that people come to me asking like is– … at JGI start with sequencing, but where else did those sequences go? Like, what are the other scientific tools we … CPI. MENAKA WILHELM: Is there anything else that you want potential users to know? TANJA WOYKE: Yeah. I think one …

… and their complex genomes are more difficult to sequence and assemble, in turn limiting the use of modern, … in these crops. For diploid species, sequencing programs generally focus on a genotype with two identical sets of chromosomes to produce a monoploid reference sequence. For the highly polyploid sugarcane, an …

… genomics existed. This is before we’re even thinking of genes and connecting genes to molecules, which is something … then genomics happened. Dan: Yeah, I did my first genome sequence with you. Brad: That’s right,  Dan: JGI did it in … made a toxin called domoic acid, [and] caused amnesic shelfish poisoning. Over 100 million dollars was lost just in …

… After I got my undergraduate degree, which was in general biology, I joined the Peace Corps. And when I was … out introns and dealing with, you know, weirdness in the sequence. You know, some clusters are not clustered…   … species”… he’s now found that some fungi have different ITS sequences in their genome, which might get you a little …

… at genomes and seeing where the really hard things to sequence were, and wondering what those … what those were … it about secondary metabolite pathways that are so hard to sequence? MARC: This isn’t true of all of them, but for … that can’t live without their host. They have no extra genes hanging around, they still dedicate 20-30% of their …

… that produces those. So it’s not a hard and fast rule, but, generally, animals do not have secondary metabolism that we … live in the root nodules of plants. And these guys were sequenced, and you can see that different Frankia have … good science for identifying secondary metabolism as we’ve sequenced more and more and more things.  ALISON: I see. …

… We focus our efforts on integrating database mining and sequence design with scaling the production of large, … We also develop methods for efficient QA/QC based on next-generation sequencing technologies including PacBio and … developing methods for converting digital information from sequence databases into biotechnological or environmental …