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… DAN UDWARY: Hey everyone and welcome back to a new session of Natural Prodcast. I’ve got two things I wanted to tell … we started to see this potential of looking for compounds based on these gene clusters. And that was my job at the … and to INDs. And it seemed as though there had been a change from when I was in industry. Because we were coming …

… Guiding Principles All staff members of the US Department of Energy (DOE) Joint Genome Institute … support our continuing contributions to advancing the research ecosystem. Their trust hinges on sustaining our … and civility in all discussions and debate; Make decisions based on merit of issues; Act honestly, transparently, and …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … to the market. And we get to say that six of those are based on natural product structures.  DAN: One of the things … knew you had a molecule. And you knew that if you made this change, which might be a small change, might be a big …

… The Fungal & Algal Program explores the vast diversity of fungi and algae to unlock their potential for bioenergy, … and bioproducts. By sequencing and analyzing the genomes of these organisms, the program investigates the biological … carbon cycling, biodegradation and biogeochemistry. This research helps translate their genomic potential into …

… Secondary Metabolites Program focuses on the exploration of secondary metabolites across bacteria, fungi, algae and … advantages to the organisms producing them, and are often involved in defense, nutrient acquisition and … roles in the environment, can unlock new avenues for bio-based products and bioenergy crop enhancement. The program …

… Research in the Woyke laboratory focuses on the utility of single-cell methods to access genetic material of uncultivated taxa of interest. One such effort is … an era of ‘homology creep’, function prediction as purely based on annotation may not be sufficient. A more recent …