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Boosting Small Molecule Production in Super “Soup”
… still work in cell-free environments? (Spoiler: Yes.) Think of cells as tiny factories: within their walls they have … report of their work, supported through the Emerging Technologies Opportunity Program at the U.S. Department of Energy … first author of the study, the lysate produced BDO at higher productivity rates than were noted inside the cell. …
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Expanding Horizons with the 2025 JGI-UC Merced Internship Cohort
… Interns contributed to a number of projects, from refining lab protocols at the bench to … One of the mentors, postdoc Yumary Vasquez, was herself a program alum from the 2022 cohort.  The UC Merced interns … she added, ”I’ve developed efficient skills in working with high performance computing and had an amazing opportunity to …
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Enlarging Windows into Understanding Gene Functions
… in sequences affect traits. In a text file, the rows of letters A, T, C and G appearing over and over in a … DNA affinity purification sequencing or DAP-seq. The technology was developed by Ronan O’Malley , who leads the … approaches of Biotin DAP-seq and multiDAP allows for ultra high throughput discovery of transcription factor binding …
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Virus Discoveries that Keep Getting Bigger
… single-cell work — have quickly accelerated understanding of giant viruses. The Science In the last thirty years, in … these viruses has enabled findings on host range, morphological structures, and infection strategies. More recently, … on the genetic makeup of new giant viruses. This review highlights four of these approaches. One way of detecting …
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Genome analyses of the carboxydotrophic sulfate-reducers Desulfotomaculum nigrificans and Desulfotomaculum carboxydivorans and reclassification of Desulfotomaculum caboxydivorans as a later synonym of Desulfotomaculum nigrificans
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Here, There and Everywhere: Large and Giant Viruses Abound Globally
… JGI-led team significantly expands the global diversity of large and giant viruses. While the microbes in a single drop of water could outnumber a small city’s population, the number … then using these sequences to make inferences about the biogeographic distribution of these viruses in the various …
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A Complex Confection Decoded: Sugarcane Reference Genome
… researchers can work toward advancing sugarcane biotechnology. The Science Considered the world’s most harvested crop by tonnage, sugarcane accounts for 80% of global sugar production. A reference genome for the … the genome required a custom pipeline and techniques. High quality primary assembly not only includes a full …
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The Case for Conservation
… purpureus is a short plant with a complex genome . Now, high-quality reference genome sequences of the male and female plants, each representing a single … highlight the multiple advances in sequencing technologies applied to the effort. The Impact Found on all …
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Massive lateral transfer of genes encoding plant cell wall-degrading enzymes to the mycoparasitic fungus Trichoderma from its plant-associated hosts
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Boosting Small Molecule Production in Super “Soup”
… Yeast strains engineered for the biochemical conversion of glucose to value-added products are limited in chemical … report of their work, supported through the Emerging Technologies Opportunity Program at the U.S. Department of Energy … first author of the study, the lysate produced BDO at higher productivity rates than were noted inside the cell. …
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Simon Roux
… Dr. Roux joined the JGI in 2017 to lead viral genomics research as part of the Metagenome Program. His responsibilities include the development of novel … B.S. in Microbiology, Université Blaise Pascal, France M.S. in Data Analysis … Blaise Pascal, France Ph.D. in Bioinformatics, Ecology and Evolutionary Biology, Université Blaise Pascal, …
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Graduate Students Get Thesis Research Opportunity at the JGI
… Twice a year, the DOE Office of Science Graduate Student Research (SCGSR) program awards graduate students the opportunity to pursue … expand with her study of microbes in California’s manmade water transport canals. “This award allows me to work … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …
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